JAY CAMPBELL

Biological Age: The Single Greatest Biomarker For A Long And Disease-Free Life

Biological age is a critically under-examined health marker for assessing your overall health and longevity.

What gets measured gets improved, and it is mission-critical to track and optimize your biological age.

After all, living longer is pointless if you are spending every waking second with chronic diseases that are ruining your quality of life.

In this blog post, you’re going to learn that your health has NOTHING to do with how old you are.

More importantly, you’ll learn why biological age is important and how you can start tracking it today.

What Is the Difference Between Chronological Age And Biological Age?

To understand the significance of biological age, it is important to understand how it is separate from your chronological age.

Your chronological age is simply how old you are — nothing more, nothing less.

And although you can be in great shape or health at any age, aging is generally considered to be a major health problem:

Aging is a complicated process characterized by progressive decline in physical, mental, and reproductive capacities, leading to a loss of function, increased susceptibility to disease, and ultimately the end of life

Which is why the field of anti-aging medicine has become so popular in recent years.

“Many natural aging mechanisms frequently result in actual diseases. From this we can conclude that fighting an aging process may well bring about an improvement of an age related illness.”

…[Anti-aging medicine] treats the underlying causes of aging and aims at alleviating any age related ailment. Its goal is to extend the healthy lifespan of humans having youthful characteristics.”

This quote hits it right on the nail: We want to live LONGER, but we also want to be HEALTHIER in the extra years we add to our lifespans.

For this reason, your chronological age is a poor indicator of aging:

“…life expectancy shows considerable variation among individuals with equal or similar CAs due to diversity in genotypes and in living habits and environments.

A 50-year-old individual may have 60-year-old body functions, and many people look older or younger compared to others at the same CA (even in twins).Therefore, CA is not an optimal indicator for the aging progress.”

Your biological age, on the other hand, dictates the speed at which you are aging:

“Biological age combines specific physiological measures to determine a person’s status of health relative to individuals of a certain chronological age.

…Biological age therefore looks at the pace at which we’re aging, and ultimately determines our current levels of health while helping to predict our lifespan.”

Biological age refers to the progressive loss of function, which is independent of time.

Researchers have discovered that we are at our healthiest when our biological age is far lower than our chronological age:

(Source)

Likewise, we are at our unhealthiest when our biological age is far greater than our chronological age.

Why Is Biological Age So Important?

Your biological age — in relation to your chronological — is heavily correlated with your likelihood of contracting multiple diseases:

Among the top 43 most common health conditions and behaviors in our cohort, after correcting for multiple comparisons, obesity, hypertension, high cholesterol, lung infection, type 2 diabetes (T2D), and breast cancer were associated with increased ΔAge in models adjusted for [chronological age] and obesity

Take a look at the picture below, which comes from the study I just quoted:

ΔAge” in this picture is defined as “chronological age subtracted by biological age”

(A positive ΔAge means your biological age is older than your chronological age, while a negative ΔAge means your biological age is younger than your chronological age)

In all 43 disease states, having an older biological age is bad news.

But the good news is that we are perfectly capable of reversing our body’s biological age:

“A small clinical study in California has suggested for the first time that it might be possible to reverse the body’s epigenetic clock, which measures a person’s biological age.

For one year, nine healthy volunteers took a cocktail of three common drugs — growth hormone and two diabetes medications — and on average shed 2.5 years of their biological ages, measured by analysing marks on a person’s genomes. The participants’ immune systems also showed signs of rejuvenation.”

Yet you don’t need drugs to make this happen.

You can easily reverse your biological age by changing your lifestyle habits and becoming fully optimized.

Things such as maintaining a healthy body fat percentage, eating a clean diet, getting regular exercise, managing stress, avoiding environmental toxins, and sleeping 7-8 hours per night can do wonders for lowering your biological age.

The conclusion is simple: Lower your biological age as much as possible and you will achieve a state of optimal health.

To use an analogy, imagine biological age as the final grade you get after taking a class.

Measuring other health metrics such as your inflammatory markers would be equivalent to the marks you get on tests and assignments that add up towards your final grade.

What Is The Best Way To Measure Biological Age?

How do we go about measuring our biological age in the most accurate and efficient way possible?

This mystery has been pursued by scientists for decades, examining different biomarkers that do the best possible job of expressing our biological age in numerical terms.

According to the American Federation for Aging Research, a biomarker for biological aging must meet four specific criteria:

1. It must predict the rate of aging. In other words, it would tell exactly where a person is in their total life span. It must be a better predictor of life span than chronological age.

2. It must monitor a basic process that underlies the aging process, not the effects of disease.

3. It must be able to be tested repeatedly without harming the person. For example, a blood test or an imaging technique

4. It must be something that works in humans and in laboratory animals, such as mice. This is so that it can be tested in lab animals before being validated in humans.

To date, the best predictor of biological age is your “epigenetic clock”:

“…the epigenetic clock appears to be associated with a wide spectrum of aging outcomes, most consistently mortality. Its predictability is observable in several different tissues, suggesting a pervasive, systems-level mechanism.”

On top of measuring the rate at which you are aging, your epigenetic clock can make a clear distinction between your chronological age and your biological age.

There are separate epigenetic clocks that can track processes such as cellular senescence.

And for those you wondering what in the world an epigenetic clock is, here’s a good definition:

“…an estimator built from epigenetic DNA methylation marks that are strongly correlated with chronological age or time, which can accurately quantify an age-related phenotype or outcome, or both

(FYI: Epigenetics refers to the study of biological processes that regulate gene expression by turning certain genes “on” and “off”)

But how is the biological process of DNA methylation connected to your biological age?

Well, it turns out that DNA methylation is largely responsible for influencing gene expression:

“DNA methylation occurs naturally when a methyl group – a chemical structure containing three carbon atoms and one hydrogen atom – attaches to one of DNA’s four nucleotide bases (adenine [A], cytosine [C], guanine [G], or thymine [T]).

The most common DNA methylation process involves the addition of a methyl group to one of the carbon atoms in the cytosine base, forming 5-methylcytosine…The majority of 5-methylcytosine is found on areas of the DNA known as CpG islands – short stretches of DNA where the frequency of the cytosine-guanine (CG) sequence is higher than other regions”

Let me tell you the implications of all that complicated science…

DNA methylation is a double-edged sword.

While it is essential to selectively turn certain genes on and off for your development in the womb and beyond, DNA methylation can also lead to several disease states.

For example, a lack of methylation (a.k.a. hypomethylation, or DNA demethylation) is commonly observed in the DNA sequences of cancer cells.

Fortunately, DNA methylation can be affected positively or negatively by our dietary and lifestyle choices.

Which leads us to asking several critical questions…

Is there any DNA methylation test in existence that can tell us EXACTLY where an excess or lack of DNA methylation is taking place in our genome?

And can this same test provide us with actionable information to determine the changes we need to start making in our lives?

The ONLY Biological Age Test You Should Be Using

If you’re looking for a truly advanced epigenetic DNA methylation test for tracking your biological age with unrivaled precision and accuracy, I would highly recommend checking out TruDiagnostic.

Taken directly from their website:

TruDiagnostic™ is a state-of-the-art epigenetics diagnostic company that offers diagnostics for clinical practitioners and their patients hoping to read their DNA methylation patterns to help diagnose and affect health outcomes.”

Since they use the most advanced deep-learning algorithms powered by artificial intelligence, you are getting your hands on a test which is far more comprehensive than anything in the market.

Whereas most tests will use 2,000 spots on the human genome or less, TruDiagnostic uses 850,000 spots — 425 times MORE than any leading competitor!

They also use blood samples, which are the best way to precisely track DNA methylation levels and provide you with better data.

But all of those things pale in comparison to the most important part of their TruAge diagnostic kit.

TruAge tells you how long you can expect to live, along with your likelihood of contracting certain diseases.

The information you get from your test puts you in a position of power to take preventative action before your health starts decaying.

This is a far-cry from common DNA testing companies such as 23AndMe and Ancestry.com, which only spit out your sequence and put the burden on you to figure out the implications.

(You’ll avoid using their inferior saliva testing methods, AND avoiding the privacy invasions frequently reported with both companies)

While other tests are certainly important, TruAge gives you a single objective measurement that provides individualized guidance for addressing your health concerns.

How To Use TruAge For The Best Results Possible

TruAge is one of the easiest blood tests you’ll ever encounter in your lifetime.

All you have to do is order the TruAge kit, which arrives at your home within 3-5 business days.

Follow the instructions on the kit and send your sample back to the TruDiagnostic lab.

Your results will be accessible online within 6-8 weeks, where you will discover your biological age and potential suggestions for lowering it.

I hate to say it, but it’s really that simple!

If you want more detailed information about how your sample gets processes in their diagnostic laboratories, go here.

Where To Order Your Own TruAge Diagnostic Kit

For all of my loyal readers and subscribers, I am offering a $50 discount when you use the code “JC50” at the checkout cart.

Simply click here and you will be taken to my landing page.

For more information about TruDiagnostic and how they plan to revolutionize medicine with their groundbreaking technology, watch this podcast I did with co-founder Ryan Smith.

If you want to dig deeper into epigenetic testing and biological aging, the blogs and tutorials on the TruDiagnostic website do an excellent job of simplifying the science.

And as always…

If you want access to the world’s best health optimization intel before anybody else finds out about it, subscribe to my email list!

The Rocket Is Officially Re-Branded As The Phoenix!

This article is being written as an emergency status update for anybody who has purchased The Rocket and is wondering what happened to their order.

Some of you have been waiting for several months and are understandably upset.

I feel your pain — like yourself, I was waiting in eager anticipation to have it in my hands.

But I can assure you that The Rocket is NOT a scam.

There were very real and legitimate reasons why nothing has happened…and why the co-founders have been silent up until now.

Before I get into all the details, let me briefly bring my newer readers up to speed.

What Was The Rocket?

A press release published a few months ago encapsulated everything The Rocket can do for men:

“…a revolutionary device from Launch Medical that uses sound wave therapy to permanently reverse symptoms of ED (erectile dysfunction).

It utilizes the same technology employed by ED clinics worldwide but has made the enhancement of sexual performance far more affordable, with a retail price of $749—while eliminating the stress, embarrassment and anxiety of conventional medical office visits.”

No downtime, no invasive surgery, no drugs, no pain, and no side effects.

This is a portable device meant to dramatically improve your sex life and enhance your sexual performance, all from the comfort and convenience of your own home.

Fuller, thicker, and possibly bigger erections await any man who uses this golden age technology.

It may be the perfect solution for men who are suffering from Peyronie’s disease or erectile dysfunction.

But it is equally effective for men who want to be as sexually optimized as possible.

Put simply: If you are a man who is active in the bedroom, choosing to own this device will greatly help your bedroom performance.

I’ve already written two high-level blog posts that talk about The Rocket in greater detail.

The first one I wrote gives you a full and complete explanation of the technology powering The Rocket.

The second one includes my personal experience with using The Rocket (and a must-see video where I do a treatment on myself).

I also have several videos and podcasts about The Rocket for people who are unaware of this life-altering device and what it can do for them:

Why Didn’t The Rocket Ship Out On Time?

My long-time readers placed orders for the Rocket in late 2019 for $399 when it first launched, and some of them paid the full price of $749 since the pre-order deadline.

Launch Medical, the company who created the product, promised to have all orders shipped out by the end of January.

But there were two major events that significantly delayed the manufacturing and delivery process.

Reason #1: COVID-19 Disrupted Manufacturing In China

Even though I have written prolifically about the spread of COVID-19, one area I did not touch upon was how the virus affecting manufacturing worldwide.

This is important because the manufacturer of The Rocket was an American-owned manufacturer based in China.

They are responsible for handling the production for several prestigious companies such as Tesla.

And they suffered a brutal decline in factory output as a result of the coronavirus:

“China’s consumer spending and factory activity fell more than expected in January and February as it fought a virus outbreak, prompting some forecasters to warn this year’s economic growth might slump to its lowest level since the 1970s.”

“…Factory output declined by a record 13.5 per cent after the Lunar New Year holiday was extended to keep manufacturing employees at home.

The unexpectedly bleak figures suggest the world’s second-largest economy is shrinking despite the ruling Communist Party’s efforts to revive manufacturing and other industries, some forecasters said.”

The value added by several manufacturing sectors in China decreased by as much as 31.8% in January to February of this year compared to 2019.

EVERY company got affected and Launch Medical was not spared from the ensuing damage.

COVID-19 was completely out of their control and there was no way to foresee its spread or its devastating impact.

Reason #2: Launch Medical Got Sued By A Major Competitor

This was a major legal setback which further delayed any possible shipment of The Rocket.

But here is what happened in a nutshell:

“Unfortunately, at this time we are unable to ship the “Rocket” product because Mark White’s company, Sexual MD Solutions LLC., the owner of GAINSWave, has obtained a preliminary legal injunction preventing the shipping of a product named the ‘Rocket’.”

For those of you who don’t know, GAINSWave is a marketing company for the high end low-intensity shockwave therapy (LIST) devices used in sexual health clinics.

The judge overseeing the case granted an injunction in favor of GAINSWave.

Here’s what this means…

The lawsuit effectively prevented any selling, marketing or licensing of The Rocket.

All of Launch Medical’s marketing materials, sales funnels, and affiliate systems CAN NOT be used anymore.

Dustin and Stephanie Wolff, the co-founders of Launch Medical, are no longer allowed to be involved in anything that bears the name “The Rocket”.

They were also barred from externally communicating with people due to the lawsuit, which is why they have been unresponsive to many customer complaints.

They were bound by the confines of the law and could not do anything about it even right now.

The one saving grace in the situation was Jon Hoffman, the PATENT HOLDER of The Rocket and the third co-founder of Launch Medical was given freedom to do whatever he wants.

The document pertaining to the public lawsuit gives Jon the legal freedom to rebrand The Rocket under a different name entirely:

“The injunction will not prohibit non-party Jon Hoffman from independently marketing and selling the Rocket under a different name…”

But Jon has now been challenged with a difficult task.

Not only can he no longer coordinate with Dustin or Stephanie, or use any of the sales materials they developed, but he also does not have access to the list of people who have already bought a Rocket.

So he has taken the necessary steps to rebrand The Rocket as The Phoenix.

As he told me in a private conversation, “The Phoenix Will Rise Again!”

I made a summary video detailing this entire situation in five short minutes:

The Immediate Future Of The Phoenix

Jon and his team have been working around the clock to get the new website up and start fulfilling orders.

That time is now:

The Phoenix is IN STOCK and Shipping everywhere including internationally..

Go Here to Purchase Yours Now:

Shop.ScorchedBird.com/jay

I am now the proud owner of The Phoenix and let me tell you.

It is AMAZING!

The Phoenix is sleek and sophisticated in its craftsmanship, and the acoustic wave technology powering it is next level.

It has a sleek “black carbon” feel to it, as if you were holding a mini-Tesla in your palms.

Check out the Un-Boxing Video!

The delays miraculously afforded Jon more time to re-engineer the manufacturing process and make some significant upgrades.

The Phoenix is even better than what The Rocket was advertised to be and EVERYONE who has ordered or will order will find out soon enough.

Any sexually active man who wants better ‘penis performance’ can purchase what I believe is one of the most amazing medical breakthroughs of our lifetime.

What Can You Do To Get Refunded And Buy The Phoenix?

Your next steps towards getting your hands on The Phoenix (in full production and shipping now) are dependent on whether you have already purchased The Rocket or not.

So I will break down my instructions into two separate categories…

Here’s What To Do If You Already Purchased The Rocket

This applies to anybody who has either:

  1. Placed an order for The Rocket at the early-bird price ($399), or
  2. Placed an order for The Rocket at its full price before mid-January ($749)

The support team for The Phoenix will absolutely, 100% be honoring any deal(purchase price) from those who pre-ordered and purchased The Rocket from Launch Medical because of my personal endorsement.

To get your refund from Launch Medical, send an email to support@launchmedical.com with your order details.

Please be patient as they are dealing with a tidal wave of refunds.

Everyone will be processed and taken care of but patience is required.

Once you get your refund, the next step is to send an email to support@scorchedbird.com that provides a photo of your receipt and explain the deal you had with Launch Medical at the time of purchase (ideally via a screenshot).

Communicate the deal you agreed upon when you purchased The Rocket and provide them with as much information as possible.

DO NOT ask them for a refund as they cannot legally process it.

They will then send you an email with a special link for you to purchase at your initial acquisition price.

They will also honor any other special deal you were offered (BOGO or additional ancillaries).

Please be patient as they continue to work through the deals and refunds.

It has also recently come to the attention of support personnel that many buyers of the Rocket are complaining their messages are not being responded by Launch Medical in a fast enough fashion.

Please make sure you are checking your spam folders as emails are responded to immediately.

I was personally asked by Jon Hoffman himself to relay his quote to my readers:

“We will absolutely honor any deals you had for a Rocket, including a free second device.

Please bear in mind that while supplies are somewhat limited due to us fulfilling orders for initial purchasers, we truly are in full production mode and will very soon have more than enough devices for anybody who ordered a Rocket previously as well as all new customers.

We are not going to let anybody keep this disruptive technology from the people who want it, need it, and deserve it.

We are democratizing erections!

Rise again!”

Here’s What To Do If You DID NOT Purchase The Rocket & Want to Purchase The Phoenix Now:

The Phoenix is in stock and shipping everywhere now!

Click Here to Purchase Your Phoenix!

To reiterate, The Phoenix support team will honor any deal that was previously made for purchasers of The Rocket.

Please be patient!

Every man looking to improve his sexual performance will want a Phoenix, and I will continue to promote it on an ongoing basis.

In the meantime, I highly recommend watching the hour-long Q&A Live Stream about The Phoenix with Jon Hoffman:

https://youtu.be/9GxwalvPBI4

Here is my most recent video demonstrating how easy it is to use The Phoenix.

And as always…

If you want access to the world’s best health optimization intel before anybody else finds out about it, subscribe to my email list!

Peptide Medicine: The Future Of Optimized Healthcare For The Next 10 Years

Therapeutic peptides are not hard-to-access compounds which can only be used by the elite for specialized purposes.

They are a revolutionary new form of medicine that can be used by anybody, no matter their age or goals.

From ultimate health optimization to treating chronic diseases, there is virtually nothing they cannot treat or fix.

Which is why they are poised to become a $65 billion market worldwide by 2026:

“Currently, there are more than 800 peptide drugs in clinical pipeline and 197 peptide-based drugs commercially available in the market.”

“The future potential of expanding peptide therapeutics market is contributed towards the characteristics like safety, targeted drug delivery and high specificity.

Especially for illnesses requiring prolonged therapy, peptides have a competitive advantage over conventional small molecule drugs.

Due to their extremely high specificity for their intended target, in combination with the fact that they are extra cellularly active, much lower amounts can be formulated.”

One biotech company is even using artificial intelligence to find therapeutic peptides that can treat COVID-19:

“Nuritas’ Peptide Finder (ΝΠΦ) Platform combines a database with years of experiments on thousands of peptides with state-of-the-art machine learning (ML) architecture that can identify peptides active against a target or pathway of interest.”

“They will have two projects focusing on COVID-19 peptide identification: one for identifying antiviral peptides that target how SARS-CoV-2 hijacks cells, and one for identifying peptides that locally reduce lung inflammation without suppressing the entire immune system.”

But where did the interest in therapeutic peptides come from?

Who came up with the genius idea to use them in the first place?

A Brief History On The Use Of Peptides In Medicine

Believe it or not, peptides have been actively used in medicine for the past 100 years:

“Starting about a century ago (World War I), the advent of the modern drug era came with pioneering therapeutic compounds like the opiate morphine and the cyclic peptide penicillin, followed in the early 1920s by the (poly)peptide insulin.”

However, small molecules were much easier to manufacture and administer for the pharmaceutical industry, which is why they were favored over peptides.

But this quickly worked against them — combined with the cost needed to bring one to the market and increasingly strict regulations, alternative solutions were needed:

“Fewer new drugs make it to the market and the patent protection of current blockbuster drugs is deteriorating, with a resulting drainage of the drug pipelines.

All this may ultimately push the pharmaceutical industry towards a new frontier in modern drug development.”

Most interestingly, peptides have also been sought out as an alternative to antibodies:

“Antibodies excel at target binding and PPI disruption with potency and specificity.

However, they carry certain liabilities, including an inability to access intracellular targets, poor tissue penetration, complex manufacturing and storage, immunogenic potential, and limitations to targets of sufficiently poor homology in host animals for B cell reactivity.”

Keep in mind that peptides are distinct from proteins, which are larger (>50 amino acids) and spontaneously rearrange into different structures.

Why Are Therapeutic Peptides So Versatile?

There are numerous reasons why peptides are being heavily used by optimization doctors who want to provide better care for their patients.

Therapeutic Peptides Treat NUMEROUS Conditions

Just take a look at this list I found of how peptides can heal and enhance the human body:

  • Increasing bone strength and density
  • Supporting joints
  • Supporting a healthy libido
  • Reducing erectile dysfunction
  • Increasing muscle strength
  • Improving sleep
  • Boosting energy levels
  • Improving fatigue
  • Supporting mood

And that’s just the tip of the iceberg.

You can also gain lean muscle, slow down aging, strengthen the immune system, increase IQ, lose stubborn body fat, and treat major diseases such as chronic inflammation, Alzheimer’s, traumatic brain injury, and much more!

Therapeutic Peptides Can Be Administered In Several Ways

While each peptide will have an “optimal” form of delivery, there are several methods for administering them.

You can inject them subcutaneously or intramuscularly.

Some of them can even be taken as an oral pill, like the muscle-building agent (small molecule) 5-Amino 1MQ.

Therapeutic Peptides Can Be Created Naturally Or Synthetically

Many of the peptides I have talked about are naturally produced by the body, which is why they tend to work so well with very few side effects.

Other peptides can be synthetically created in a lab, and many leading research teams have worked tirelessly to make them in a way that is both quick and cost-effective:

What Stops Therapeutic Peptides From Going Mainstream?

Bluntly, therapeutic peptides are simply too competitive with traditional pharmaceutical drugs.

They work far better for treating certain conditions and come with fewer unwanted side effects.

This would directly compete with existing revenue streams, which is why certain actions are taken to ensure they don’t reach widespread use.

One example of active suppression involves approving a peptide for an extremely narrow use while targeting doctors who are using them for off-label purposes (i.e. their REAL purpose).

I have written extensively about this topic in a very recent article of mine.

But the Clinical Peptide Society does a great job of summarizing the FDA’s efforts to ban peptides:’

“Unfortunately the FDA has implemented regulatory changes in the definition of a peptide less than 40 amino acid long and a ‘biological product’. 

One compound pharmacy has been restricted in compounding peptides like BPC-157, MOTS-c, Semax and other peptides. 

It is predicted that other compound pharmacies will no longer be able to compound peptides since the peptides are not on the Bulk Compounding List (503a) although they have been nominated to be on the list.”

Doctors are fighting to enact policy change that allows the use of peptides for medical purposes, as the FDA is purposely rushing very few hearings without any public input.

The best way for you to help them is to visit SavePeptides.org and have your voice heard!

A Few Therapeutic Peptides You MUST Know About

To tell you about every single therapeutic peptide in existence would be going way beyond the scope of this article.

That privilege is being reserved for my upcoming therapeutic peptide book being released this year.

But in the meantime, here are some of the most prominent ones worth your attention…

Peptides For Fat Loss

AOD9604, short for “Advanced Obesity Drug”, is a modified form of amino acids #176-191 at the C-terminus of the human growth hormone (hGH) peptide.

Making up less than 10% of the total peptide, this small section appears to control the fat-reducing effects attributable to hGH.

In other words, AOD9604 induces fat loss without the side effect of insulin resistance (seen in many other peptides that stimulate growth hormone).

Tesamorelin and Ipamorelin are BY FAR the best two medications in existence for losing stubborn body fat, and I have extensive experience with using both peptides.

I made an in-depth YouTube video with step-by-step instructions for how to use them together:

Peptides For Muscle Gain

PEG-MGF (Pegylated Mechano Growth Factor) is a promising peptide for hormonally optimized people who want to add a big “boost” to their lean muscle gains.

To describe what it does in a single sentence: “It significantly improves recuperation, can help minimize the effect of DOMS, and also elicit increased protein synthesis for muscle hypertrophy.”

5-Amino 1MQ works by targeting NNMT (small molecule nicotinamide N-methyltransferase), which has a role in the regulation of nicotinamide (NA) and of the methionine cycle.

NNMT inhibition activates muscle stem cells and promotes the regeneration of aged muscle cells.

I have put on 9 pounds of lean mass after four weeks of using it, with ZERO changes to my current diet or training schedule.

Peptides For Skin Care

No other peptide deserves to be here more than GHK-Cu.

It Improves skin density and firmness, reduces fine lines and deep wrinkles, dramatically improve skin clarity, and tightens loose skin.

Many of my friends have noted its ability to treat sunburns, which is great for those of us who are fair-skinned.

GHK-Cu is a topical solution that works systemically, as you can apply it to any part of your body and heal the site of injury (no injections necessary).

I like this Peptide so much that I co-founded Aseir Custom to sell it.

Even better is that GHK-Cu combined with C-60 revolutionary regrows hair. (Our product is currently in the pipeline and arriving soon)

AseirCustom-GHK-Cu-ReGrows-Hair

Peptides For Wound & Injury Healing

BPC-157 has been a favorite of mine, so much so that I have dedicated an entire article to this peptide.

As I said in the article, It is extremely protective of numerous bodily systems, on top of possessing the ability to radically accelerate the healing process of several types of injuries [such as muscles, bones, tendons and ligaments].”

TB-500 is another healing acceleration recovery peptide which is slightly better than BPC-157 for healing muscle injuries.

Just like BPC-157, it can be injected anywhere in the body (rather than directly at the site of injury).

Since both peptides work synergistically, you can take them at the same time and further speed up your body’s natural rate of healing.

Peptides For Improving Cognition

Dihexa is a powerful peptide derived from angiotensin IV that can actually repair brain damage instead of slowing down the rate at which it happens.

It is SEVEN TIMES more potent than BDNF, a neurochemical essential for forming new neural connections in the brain and allowing us to take in new information.

Not only can it potentially be used for treating Alzheimer’s, but it can also increase your mental stamina and long-term memory.

Semax is a ridiculously powerful nootropic, but it’s also cardioprotective, neuroprotective, neurorestorative, a powerful immune booster, and a nifty way to treat optic nerve disorder.

Like Dihexa, it can also lead to a big boost in the brain’s BDNF levels.

Its analog, N-Acetyl Semax, is a much more powerful variant due to its ability to cross the blood-brain barrier with greater ease.

Peptides For Sexual Health

PT-141 (a.k.a. Bremelanotide, “Vyleesi”) is a synthetic melanocortin analog that is derived from Melanotan 2 and is known as the world’s first FDA-approved aphrodisiac. (I will have an article that dives deeper about the merits of PT-141 in the coming weeks.)

Unlike other drugs meant for sexual health, it targets the region of the brain responsible for regulating sexual response, which makes it useful for both men and women.

But for the men reading this, it is phenomenal at increasing erection strength and duration.

Every Single Peptides Podcast I Have Ever Done

No blog post on peptides would possibly be complete without mentioning every single podcast I have ever done on the subject.

So here they are!

Why Peptides Are the Future of Medicine w/ Ryan Smith

This was the podcast that started my deep exploration into the world of therapeutic peptides. (I had been a user of Ipamorelin since 2007).

Although I had previously written about some of them in The TOT Bible, it wasn’t until meeting Ryan Smith of Tailor Made Compounding that I went all in.

I highly recommend watching the entire thing, but to sum it up in two sentences:

“They are the future of medicine because of just how many health and optimization problems they can solve.

Peptides are great because they don’t have many side effects from a metabolizing standpoint, and you don’t have to worry about drug interactions.”

Recap of the International Peptides Society Conference with Carl Lanore

I was privileged to attend the International Peptides Society Conference on August 9th-10th, 2019.

While I wasn’t able to share all of the proprietary high-level information presented in the conference, that doesn’t mean I didn’t give away some golden nuggets. 😉

Watch this podcast if you want to know more about therapeutic peptides than most doctors do!

High-Level Peptide Recommendations for Superhero Performance w/ Dr. Elizabeth Yurth

Dr. Yurth jones me in a deep-dive interview to talk about how she has successfully used peptides to treat older patients for issues such as bone degradation.

I highly recommend sharing this podcast with anyone in their late 40s and above!

The Peptide Revolution in Modern Medicine w/ Dr. William Seeds

Considered one of the top peptides experts in the world, Dr. Seeds was fortunate enough to share exactly how peptides will change the future of healthcare.

As I wrote in the podcast description:

“Peptides aren’t about cheating the health code or enhancing performance, they are about repairing and restoring our bodies.

Every aspect of our bodies and our health can be completely changed by peptides. “

All You Ever Wanted To Know About Peptides But Didn’t Know How To Ask

What you’re about to see is an incredibly comprehensive FAQ where we answer multiple questions about peptides.

If you have any thoughts or concerns about the therapeutic use of peptides, there’s a 99% chance this video will answer all of them.

A Physician’s Assistant’s Perspective On Peptides & Optimization w/ AJ Piovesan

It was a real pleasure to talk with a physician’s assistant and get their in-the-field perspective on treating patients with peptides.

My favorite takeaway from this podcast was how peptides are superior to growth hormones, and why anyone who says otherwise is either using them wrong or taking “fake” peptides.

The Best Podcast EVER DONE on Using Therapeutic Peptides

Joined by Ryan Smith and Blake McLeod from Tailor Made Compounding, I gave my viewers a state-of-the-science overview on therapeutic peptides to kick off 2020.

Many of these peptides are ones you will NOT see in any of my written materials (until my peptides book releases later this year).

We discussed how much to take, how to cycle them, what they’ll cost you, and who should (or should NOT) be using them.

How To Use Peptides To Boost Immunity, Heal, Burn Fat, Build Muscle, Increase IQ & Slow Aging!

Last and certainly not least, here is the EPIC podcast between myself, Nick Andrews, Ryan Smith, and notable biohacker Ben Greenfield.

This is nearly 2 hours of golden age intel that rivals anything else you will find online regarding peptides, both new and old.

If you want to go through the entire transcript instead, click here.

Where Do Therapeutic Peptides Go From Here?

I wish I could give you an optimistic answer to this question.

As I mentioned earlier, there is an ACTIVE effort by Big Pharma and other higher powers to actively suppress therapeutic peptides into non-existence.

I can’t even say for sure what will happen next.

The powers that be may banish them into the black market.

We may also see a united revolution where physicians, biohackers, and patients in the health optimization community unite to keep peptides in circulation.

All I will say is this: Without an active fight, the future of therapeutic peptides is uncertain.

It is up to each and every one of us to speak up.

Read every single one of my articles and watch all of my podcasts on the subject.

Share them with your friends, family, and healthcare workers to spread the good word.

Educate yourself on how just one of these peptides could completely change the trajectory of your life by reading The TOT Bible or Living A Fully Optimized Life.

My new peptides book coming out later this year will be nothing short of groundbreaking and I truly hope it sparks a MASSIVE international movement.

If you want to see snippets from the book as it is being written in real-time, make sure you join my email list!

Every single Monday email will feature a new peptide being added to the book until its eventual release to the public.

Remember:

Raise Your Vibration to Optimize Your Love Creation

Estrogen Blocking: The REAL Reason Why Competitive & Amateur Bodybuilders Are Dying

Professional and Competitive Bodybuilding has to be one of the most dangerous sports in existence, and a large part of that is due to estrogen-blocking.

What other sport has a 34% HIGHER death rate than the average American male?

“Daniel Gwartney, MD, and colleagues at Baylor College of Medicine in Houston identified 1,578 professional male bodybuilders who compete from 1948 to 2014. They were able to obtain complete mortality data for 597.” 

“…Of the 597 men, 58 (9.7%) were reported dead. Only 40 deaths were expected in this population based on age-matched data, for a standardized mortality rate of 1.34. The mean age of death was 47.7 years (range 26.6 – 75.4 years).”

The saddest part about all this is how bodybuilders consciously KNOW and ACCEPT a fate that involves early death:

“In the 1980s, Dr. Robert Goldman began asking top-level athletes if they’d accept a proverbial deal with the devil that guaranteed victory in every competition they entered… but also guaranteed their death within five years.

Goldman consistently found that the majority of athletes would eagerly accept the deal. It became known as ‘Goldman’s Dilemma.’”

Let me be as clear as possible in saying this…I DO NOT endorse the lifestyle of most competitive body builders.

As a former physique competitor myself (winner of various NPC contests and having consulted with numerous aspiring and pro bodybuilders over the last 2 decades)

I have massive respect for the amount of work, both in and out of the gym these men(and women)put in to build their phenomenal stage worthy physiques.

I consider it an honorable mission to help minimize the number of unnecessary bodybuilding injuries and deaths.

This will allow these competitors to live longer and hopefully maintain some level of fully optimized health.

The best way I can help is via presentation of the scientific evidence in combination with the empirical evidence of prescribing doctors who have thriving and healthy patients.

Both of which unequivocally prove aromatase inhibition is toxic to male health.

Therapeutic Testosterone Works So Damn Well BECAUSE Of Estrogen

If you read my previous article on the dangers of suppressing men’s estrogen levels, you already know the answer.

For those of you who don’t, allow me to summarize it in a single sentence:

Testosterone MUST be converted into the pleiotropic hormone estradiol “E2” (via the aromatase enzyme) to manifest its numerous therapeutic benefits to biological systems.

You know all the 600+ studies I cited in The TOT Bible regarding all the positive health effects of therapeutic testosterone?

News flash: Not a SINGLE STUDY involved blocking or suppressing estrogen levels in any of the studied test subjects.

As I’ll discuss later on in this blog post, estrogen is essential for bone strength, heart health, and a wide variety of important biological functions.

Furthermore, estrogen has been falsely labeled as a “female sex hormone” when it is just as crucial for optimal male sexual health:

“…estradiol, the predominant form of estrogen, also plays a critical role in male sexual function.

Estradiol in men is essential for modulating libido, erectile function, and spermatogenesis.

Estrogen receptors, as well as aromatase, the enzyme that converts testosterone to estrogen, are abundant in brain, penis, and testis, organs important for sexual function.”

For this reason alone, there is no such thing as ‘estrogen dominance’ or ‘high estrogen symptoms’.

What you’re really looking at is a potential deadly combination of high body fat, chronic inflammation and insulin resistance working together to KILL YOU!

Your Body IS NOT Designed To Function At Clinically Low Estrogen Levels

What 99% of physicians fail to realize is that the body has a natural fail-safe mechanism to ensure an optimal balance of testosterone and estrogen.

This mechanism comes in the form of the aromatase enzyme I talked about earlier:

“Aromatase is a specific component of the cytochrome P450 enzyme system responsible for the transformation of androgen precursors into estrogens.

This enzyme is encoded by the CYP19A1 gene located at chromosome 15q21.2, that is, expressed in ovary and testis, but also in many extraglandular sites such as the placenta, brain, adipose tissue, and bone”

In other words, the correct testosterone-to-estrogen ratio for YOUR body is already genetically encoded and in constant regulation.

Everyone’s “sweet spot” is entirely dictated by biochemical individuality (due to your genetics) and your epigenetics (a.k.a. your lifestyle).

Therefore, attempting to get your estradiol (E2) levels to conform within ranges set forth by laboratory standards is a big fat waste of time.

(And by the way…the mean ranges provided by LabCorp and Quest Diagnostics are NOT designed for men using therapeutic testosterone!)

Blocking the aromatase enzyme is a terrible idea because you’re preventing your body from reaching a state of hormonal equilibrium between testosterone and estrogen levels:

“Men with estrogen deficiency caused by a mutation in the CYP19 gene suffer from low bone mineral density (BMD) and unfused epiphyses, and have high gonadotropin and testosterone levels.

As you can see, there are multiple disease pathologies possible when a genetic mutation causes estrogen deficiency.

Which leads me to the main takeaway of this section…

Anytime estrogen is attenuated, lowered, or blocked, pathology develops because estradiol is very protective in men.

Never-Block-Your-Estrogen

Most of the beneficial effects of therapeutic testosterone are MODULATED by estradiol!

As one of the world’s leading Androgen Researchers and epidemiologists, Dr. Scott Howell has spent the last 2 decades pouring over tens of thousands of studies and has made the same discovery.

Specifically, he came up with five main conclusions:

1. Optimal cellular physiology of sex steroid target tissues vitally depends on the androgen-to-estradiol ratio rather than single hormone action in isolation.

2. This ratio is controlled in vertebrates by aromatase enzyme levels set through the aromatase gene.

3. Alteration of this ratio in either direction leads to pathology of most organ systems.

4. Aromatase is a fail-safe mechanism in men to protect organ systems through the needed levels of estradiol for organ protection relative to circulating endogenous or exogenous androgens.

5. Only 20 cases of true aromatase deficiency or true aromatase excess syndrome has been described in the medical literature since 2014 so there is no justifiable reason to block aromatase in men on testosterone replacement or bodybuilders taking massive amounts of synthetic androgens.

Aromatase Inhibitors: Dangerous Medications You Should Stay Away From

Aromatase inhibitors (AIs) are the #1 go-to drug for any physician who wants to suppress estrogen levels in men.

How they work is very straightforward:

“Aromatase inhibitors and inactivators interfere with the body’s ability to produce estrogen from androgens by suppressing aromatase enzyme activity.”

If you refer to the diagram I posted earlier in the article, this will make sense right away.

By blocking the ability of aromatase to convert testosterone to estrogen, you have more testosterone and less estrogen.

Strangely enough, AI’s were specifically formulated for the treatment and prevention of invasive breast cancer in women.

It wasn’t until the 80s when legendary steroid guru Dan Duchaine popularized the use of AIs for bodybuilders injecting copious amounts of anabolic steroids:

“Male bodybuilders started using Nolvadex and Proviron to combat the aromatization (estrogen conversion) of high dosages of anabolic steroids.”

It must be working; bodybuilders will quickly abandon a drug if there is no bang for the buck. I’ve dieted with and without Nolvadex, and I lost fat faster with Nolvadex.”

Even though he dedicated an ENTIRE chapter to using anti-estrogenic drugs for removing stubborn lower body fat, his conclusion was nothing short of interesting:

“In the grand hierarchy of diet drugs, anti-estrogens are now considered below average.

Certainly, you will get better effects with clenbuterol, yohimbe, ephedrine and phenformin. After all of these, choose Nolvadex or Teslac.

Although anti-estrogens can be helpful for a variety of other maladies, they are an unnec­essary luxury for dieters.”

It was thanks to Dan that the emerging issue of “high estrogen symptoms” became so dominant in bodybuilding circles.

Ironically, even breast cancer patients are increasingly avoiding the use of AIs to treat breast cancer:

“This meta-analysis confirms that an aromatase inhibitor (AI) is not the best therapy for all postmenopausal women with hormone-receptor positive, early-stage, breast cancer. 

This potentially practice-changing article provides new evidence for AI toxicities, which practitioners should consider when choosing between adjuvant endocrine therapies for postmenopausal breast cancer patients.

The authors conducted the study to clarify why AIs, when compared with tamoxifen, increased disease-free survival but not overall survival.

AI toxicities were suspected to counteract decreased recurrence rates.”

Here is just a small sample of some of the side effects which come with the use of AIs:

  • Increased intra-abdominal fat
  • Sexual dysfunction
  • Breast swelling or pain
  • Thinning hair
  • Insomnia
  • Extreme fatigue

Looks like Dan Duchaine was half right — there ARE better drugs you can use if you are serious about getting shredded as fast as possible!

The Numerous Health Benefits Of Leaving Aromatase Alone

I mentioned the health benefits of estrogen earlier, but I want to examine another worthwhile yet related topic.

Namely, why is it in our best interest to leave the aromatase enzyme untouched?

There are numerous reasons why we should let Mother Nature handle things, as revealed in a major review examining the connection between aromatase deficiency and various facets of health…

  • Cognitive Health: Estradiol is neuroprotective, and is also essential for mood stabilization and normal sexual behavior in males.
  • Biologically Protective: In the same study cited above, estradiol was shown to be protective of both the immune and cardiovascular systems.
  • Lower Body Fat: Aromatase deficiency is correlated closely with increased visceral body fat
  • Better Metabolism: Men with true aromatase deficiency have insulin resistance and impaired carbohydrate metabolism.
  • Healthier Lipid Profile: Aromatase deficiency usually leads to lower levels of high-density lipoprotein cholesterol — also known as the “good” cholesterol — and elevated triglycerides

(As a sidebar, oftentimes a precise course of estradiol treatment can fully resolve this)

Bone Density: Aromatase deficiency is associated with lower body mineral density and stunted bone growth.

This study was published 14 years ago in 2006, and even they were fully aware of the adverse health outcomes associated with using AIs!

Two Common Bodybuilder Side Effects Wrongly Blamed On Estrogen

Even with all of the information above, bodybuilders will commonly blame high levels of estrogen for two side effects they commonly experience.

So let’s debunk both of them really quick…

Water Retention

Testosterone and other androgens (i.e. male sex hormones) are able to retain elements such as sodium, nitrogen and calcium.

Testosterone can also increase the production of anti-diuretic hormone (ADH) through an aromatase-dependent mechanism, while estradiol decreases ADH production in a dose-response manner.

(FYI: ADH is responsible for maintaining electrolyte balance and controlling how much water your kidneys should hold)

This means that testosterone is responsible for conserving bodily water and preventing fluid loss.

And therefore it does not make sense to say that estradiol is responsible for water retention.

Here’s the really interesting part about androgen-related water retention:

It is mediated through local renin-angiotensin system activation in the kidneys and ADH.

In plain English, estrogen is not the problem here.

Any supposed issues around water retention will resolve in 4-6 weeks.

However, it will recur if someone consumes a diet high in sodium and/or carbohydrates and also has high systemic inflammation and visceral body fat from living a poor lifestyle.

Vasomotor Symptoms

Despite what you may have heard, the vasomotor symptoms experienced by women are also present in men:

“Vasomotor symptoms are those that occur due to the constriction or dilation of blood vessels.

They include hot flashes, night sweats, heart palpitations, and changes in blood pressure.

The most likely reason why these symptoms can occur during menopause is that hormonal fluctuations affect the mechanisms that control blood pressure and temperature control.”

One side effect which wasn’t mentioned above are emotional and mood disturbances, which are often tied with so-called estrogen dominance.

<Remember there is no such thing as estrogen-dominance, only insulin resistance and systemic inflammation>

This was disproven in a 2016 study examining two separate cohorts of men with low testosterone from two separate yet randomized trials.

The main purpose of the study was to see how testosterone and estradiol deficiency contribute towards the development of vasomotor symptoms.

One cohort received either a placebo or various doses of testosterone gel for 16 weeks.

The other cohort received either a placebo or the same doses of testosterone gel AND anastrozole (a popular AI) for 16 weeks.

What was the key mediator of vasomotor symptoms?

A LACK of estrogen!

Furthermore, the incidence of vasomotor symptoms was most present in the men who were taking the AI.

This is the best evidence we have to date, and as anybody knows, anecdotes in the bodybuilding industry never really pan out.

The Medical Community Does NOT Understand The Harm Of Blocking Estrogen

To this day, I am still astounded by the number of clinicians who do not READ modern scientific literature and have no clue how to interpret it properly.

Yet many of them will still assert that blocking estrogen is the way to go.

You can’t simply come to this conclusion after reading 1-2 studies and talking to a few “bros” in the gym.

Dr. Scott Howell, one of the foremost world leaders on managing estrogen levels in men, knows FOR A FACT that aromatase should not be inhibited in otherwise healthy men.

In fact, blocking aromatase is extremely harmful in the long run if you are using androgens.

How did he come to this conclusion?

Very simple…

He looked at the totality of the evidence: Animal or mammal studies, case reports, forensic reports, observational studies, dose-escalation studies, toxicology studies, and designs that are closely related.

Dr. Howell also spent 10 years reviewing and compiling case and forensic reports from all over the world, looking at observational studies, trials, and experiments that were conducted on anabolic steroids.

In about a 15-year period, he compiled nearly 30,000 androgen studies from the early 1900s to the present day.

He found that there was NO SUCH THING as a universal “sweet spot” for estradiol levels in men.

This misguided notion came from a single study published in 2001 that examined 63 men with severe male factor infertility.

What you would discover upon reading the paper more closely is how many of them had other comorbidities:

  • 16 men had Klinefelter’s syndrome (born with an extra “X” chromosome, leading to infertility)
  • 14 had varicocele (enlarged veins inside your scrotum, lowering sperm production)
  • 12 were idiopathic (having diseases or genetic conditions that arise spontaneously for unknown reasons)

Their FSH (follicle-stimulating hormone) levels ranged from 10.0 to 39.1, averaging out at 21.2.

This population was obviously very sick, and yet these researchers thought their testosterone-to-estradiol ratios could be used as reference points:

“We identified an endocrinopathy in men with severe male factor infertility that is characterized by a decreased serum testosterone-to-estradiol ratio.

This ratio can be corrected by aromatase inhibition, resulting in a significant improvement in semen parameters in oligospermic patients.”

The ratios found for these sick men are only applicable to them specifically and nobody else.

You CANNOT take the results from this very niche population and apply them to otherwise healthy men, especially those who are using therapeutic testosterone.

It only shows the ignorance of research methods among clinicians who make this rookie mistake, thereby causing harm to their patients.

So WHY Are Professional Bodybuilders Dropping Dead?

We now arrive at the million-dollar question: How is estrogen-blocking connected to the premature deaths of untold numbers of bodybuilders?

They died from a combination of supraphysiologic dosages of anabolic-androgenic steroids (AAS) and high dosages of AIs.

How do we know this for certain?

We can see it through the number of forensic case reports involving bodybuilders who drop dead from myocardial infarction and heart failure:

“Taking steroids can cause the left ventricle, the main pumping chamber of the heart, to enlarge disproportionately compared to the rest of the heart. This increases chances for irregular heartbeats and sudden death”

And as Dr. Howell put it, “The pathology is characteristically a diffuse collagen infiltration that occurs simultaneously with left ventricular hypertrophy and it happens across the board when estrogen is blocked.”

But I want to dive deeper into this and talk about the five main reasons why bodybuilders are constantly dying of heart problems.

Overloading The Heart Muscle Through Uncontrolled Hypertension

Our heart changes in size, shape and function through a process called “cardiac remodeling.”

Physiologic remodeling takes place when an athlete exerts vigorous effort and it is not considered to be damaging.

Pathologic remodeling, however, takes place when the heart muscle sustains some form of injury.

When you take extremely high doses of AAS and combine them with several hours of exercise per day, you get hypertrophy of the heart’s left ventricle (and the heart overall).

Here’s what I mean…

The physiologic androgens normally found in your body are known to have anabolic effects on your heart cells.

When you “knock out” the receptors these androgens normally bind to, and there is no presence of estradiol produced by aromatase, cardiac growth (i.e. heart growth) does not take place.

However…when you “knock out” the aromatase enzyme, mice studies have shown that the androgens stimulate MORE hypertrophy of the heart muscle.

That’s not where the story ends, especially since you’re using supra-physiologic doses of AAS.

The cardiac remodeling that then takes place involves a peptide known as angiotensin II, which belongs to the Renin-Angiotensin-Aldosterone System (RAAS).

Angiotensin II is responsible for increasing blood pressure by constricting your blood vessels, and is also involved in pathologic cardiac remodeling.

In this remodeling process, an overproduction of collagen (a structural protein found in connective tissues) takes place and the excess gets stored in your heart and arteries.

So let’s recap…

When you have elevated Angiotensin II levels and low estradiol levels, you have uncontrolled hypertension.

That right there is the perfect recipe for cardiac pathology in bodybuilders because you have lost the protection to EVERY organ system offered by estradiol.

When bodybuilders use high-dose androgens and aromatase inhibitors, the cardiac pathology becomes even more extreme in terms of hypertrophy and collagen infiltration.

Put another way, Angiotensin II is a bodybuilder’s worst enemy.

Angiotensin II also increases the synthesis and release of 20-HETE in the kidneys, which is also a potent vasoconstrictor and pro-hypertensive within the blood vessels of the heart.

Blocking Aromatase Prevents Estrogen From Exerting Cardio-protective Effects

Estradiol (E2) is able to counter the pathologic hypertrophy induced by androgens by binding to estrogen receptor beta (ERβ), and the collagen remodeling by binding to estrogen receptor alpha (ERα).

Allow me to summarize what happens with each receptor in greater detail.

When estradiol binds to ERβ in heart muscle cells, it can:

When estradiol binds to ERα in heart muscle cells, it can:

In summation, E2 binding to ERβ and ERα in heart muscle cells is essential to maintain cardiac health.

High doses of androgen will lead to adaptive cardiac hypertrophy that is somewhat reversible, but only if pathologic fibrosis does not occur.

But in the absence of E2 binding, the adaptive hypertrophy from androgens is magnified and begins the progression to pathologic remodeling.

Fibrosis will occur if nothing is done to resolve the underlying stimulus early on during androgen abuse.

Or as Dr. Howell put it: “When high dose androgens are coupled with aromatase inhibitors, progressive fibrosis becomes a critical pathological event in the progression to cardiac hypertrophy and loss of cardiac function.”

Excessive Oxygen Demands From An Unnatural Amount Of Muscle Tissue

As a logical consequence of the first two outcomes, you end up putting a LOT of residual strain on your heart.

Because you’re using supra-physiologic doses of AAS, you are carrying an additional 50-100 pounds of lean muscle tissue (relative to what your natural genetic weight would be).

This leads to an unnatural demand for oxygen from the tissue:

“Myocardial oxygen demand is the amount of oxygen that the heart requires to maintain optimal function, and myocardial oxygen supply is the amount of oxygen provided to the heart by the blood which is controlled by the coronary arteries.”

How long do you think your heart can keep up with the endless need to supply every tissue with the required amount of oxygen for optimal function?

It can’t pump enough blood, and it cannot do so fast enough to keep the body going.

And the end result is some kind of heart failure.

The Bodybuilder Lifestyle Makes All The Heart Problems So Much Worse

With hours of heavy resistance training, you are further inducing the cardiac hypertrophy mediated by Angiotensin II and the excessive doses of androgens used.

This has been a consistent finding in case studies involving bodybuilder deaths:

“Our findings support an emerging consensus that the effects of vigorous weight training, combined with anabolic steroid use and increased androgen sensitivity, may predispose these young men to myocardial injury and even sudden cardiac death”

In virtually every single story of a bodybuilder passing away, a heart problem always seems to be at the very root of what caused their untimely death:

“…in all cases the autopsy findings together with the histological examination have highlighted cardiac causes of death.

Only in one case  a mechanical cardiovascular cause of death was found (a bilateral pulmonary embolism from deep venous thrombus of lower extremities).

In numerous cases, a common finding was a left ventricular hypertrophy, frequently associated with fibrosis and myocytolisis.”

I think the takeaway so far is fairly obvious.

Supra-Physiologic Dosages of Anabolic Steroids Cause Damage To The Cardiovascular System

Putting aside the estrogen talk for a moment, the androgens being used by bodybuilders come with their own host of damaging side effects.

Here are some of the possible cardiotoxicity outcomes I was able to dig up…

  • Loss of heart function
  • Cardiomegaly (an enlarged heart that arises from the heart being overworked or damaged)
  • Hardened arteries
  • Reduced ability to pump blood uniformly throughout the body

One key point to mention is that the majority of the cardiac changes can be reversed, or even prevented.

The exception that will not reverse is collagen infiltration between cardiomyocytes (heart muscle cells) and arteries that leads to pathologic remodeling.

And that’s not even getting into how the other biological systems in your body are impacted…

The interesting part about all this is that the literature enabled the identification of specific toxicity phenotypes in each of these categories.

Each form of toxicity also has a direct injury component through reactive oxygen species and oxidative tissue damage.

How Physicians Can Start Saving Bodybuilders’ Lives

The funny part about solving this issue is how remarkably simple the solution is…

You need to give your body a few weeks to fully adapt to the exogenous administration of testosterone.

All of the symptoms you experience will eventually be resolved and you will be at a new normal.

The only way you would end up having a legitimate insensitivity to testosterone is if you had an extremely rare genetic disorder where your androgen receptors are mutated.

We’re talking about 0.001% of the population — if this is you, you would have known by the time you/ were 5 as your “development” would have been way off.

You need to stop obsessing about hour-to-hour mood changes, and instead evaluate your mood over a longer period of time (I’m talking about 2-3 months here).

Testosterone is NOT a magic bullet and it will not change everything.

This is why tip-of-the-spear physicians encourage new patients on therapeutic testosterone to “ride it out” for a few weeks before making any changes.

Any necessary changes would rarely IF EVER consist of adding an AI to suppress or modulate your estradiol levels.

The right changes are cleaning up your lifestyle (reducing systemic inflammation) and most importantly dropping visceral body fat.

With all this in mind, there are two immediate steps clinicians can take to reduce harm in anabolic steroid users…

1) Take an Angiotensin-converting enzyme (ACE) inhibitor or an Angiotensin Receptor Blocker (ARB).

The two enzymes ACE and ACE2 are responsible for regulating your body’s production of Angiotensin II.

As you already know, elevated levels of Angiotensin II are detrimental to the function of the heart and kidney.

Angiotensin II is made from cardioprotective Angiotensin I through ACE, and so we want to use ACE inhibitors to block this conversion.

Conversely, using an ARB will prevent Angiotensin II from binding to its receptors and exerting its effects.

2) AVOID using AI’s altogether, (if removal due to extreme psychogenic need purposes is impossible)only using them for very short periods of time (2-3 weeks MAX) where goal is permanent titration of therapy)

If you are a man working with a Doctor who has you on an AI, find another Doctor ASAP.

If you are a Bodybuilder utilizing AI’s to limit your ‘perceived side effects’ from supra-physiologic levels of AAS, make sure you read this article over and over again.

I have also written prolifically on the dangers of using AIs on this website.

In addition, you will be doing yourself a massive disservice if you don’t watch the podcast I did with Dr. Scott Howell on the harm of aromatase inhibition.

Make sure you read through all these materials as many times as necessary to understand the danger you are placing upon your biological systems and lifespan.

Having helped many bodybuilders regain control of their health without sacrificing their physique goals, Dr. Howell gets my highest recommendation.

Email him at showell@tier1hw.com for inquiries regarding harm reduction consultations and DNA analysis.

And as always…

If you want access to the world’s best health optimization intel before anybody else finds out about it, subscribe to my email list!

How (And Why) Therapeutic Peptides Are Being Suppressed Into Non-Existence

Therapeutic peptides will be the most talked-about medical treatment in the coming decade, IF they are still around for the next 10 years from a legal and clinical perspective.

Especially since they have several advantages over other forms of medication:

“Therapeutic peptides have several important advantages over proteins or antibodies: they are small in size, easy to synthesise and have the ability to penetrate the cell membranes.

They also have high activity, specificity and affinity; minimal drug-drug interaction; and biological and chemical diversity.

An added benefit of using peptides as a treatment is that they do not accumulate in specific organs (e.g. kidney or liver), which can help to minimise their toxic side effects.

They can also be rapidly synthesized and easily modified and are less immunogenic than recombinant antibodies or proteins.” 

(FYI: Peptides are categorized as having a chain of 40 amino acids as less, whereas anything more is considered as a protein/antibody)

And since they show great promise in treating a never-ending spectrum of diseases, there is no reason to NOT promote them relentlessly.

But there are some higher powers who have a vested interest in ensuring they never see the day of light.

And if they do, they will be for treating conditions far beyond the scope of their true value.

This sounds like an extraordinary claim if you take it at face value.

Which is why I’m going to take my time and slowly explain how peptides are fading away from clinical use.

Why I’m Focused On Preserving The Peptides Industry

So here’s what has happened in recent times…

One of the world’s most prestigious peptide compounding pharmacies has been put on notice.

They received a ‘warning letter from the Federal Drug Administration (FDA)’ stating that some of the peptides they’ve been prescribing are being taken off the market as they are not FDA-approved:

That’s right – they’ve been synthesizing massively life-enhancing therapeutic peptides for the past 3 years, but no more.

This compounding pharmacy will have to stop producing these select peptides by a certain date to comply with the FDA mandate.

Why would the FDA do this?

If their primary mission is to protect consumers, globally and in the USA, why would they stop the distribution of proven and powerful life-altering medications that can save human lives?

To answer this question, we need to do some deep digging into several topics…

What Are Compounding Pharmacies And Why Do They Exist?

In case you have never heard of a compounding pharmacy, here is a brief description of what they do:

“Compounding is the creation of a pharmaceutical preparation—a drug—by a licensed pharmacist to meet the unique needs of an individual patient (either human or animal) when a commercially available drug does not meet those needs.

A patient may not be able to tolerate the commercially available drug, the exact preparation needed may not be commercially available, or a patient may require a drug that is currently in shortage or discontinued.”

Historically, there used to be a time in history where all drugs were compounded.

You would visit your local apothecary and the pharmacist would make it for you.

Doing so would allow the pharmacist to customize your formulation in a way that best suits you:

  • Adding flavors to make a drug more digestible (think of a child who hates taking medication)
  • Increasing or reducing the strength/dosage
  • Removing certain allergens you may be sensitive to
  • Altering the medium of the medication (taking a liquid instead of a pill, for instance)

Up until the 1900s, this was the very essence of the pharmacy field.

All of this changed when the Industrial Revolution came about and led to the mass manufacturing and production of standardized formulations.

So if a prescribed drug came in a dosage strength that was too high/low for you, or it had an additive you were allergic to, you were out of luck.

However, there still remained people who had specific and individualized medical needs.

For this reason, compounding pharmacies still existed but were largely left to the wayside.

It is only in very recent times where compounding pharmacies have begun to emerge again:

Funny how history ends up coming full circle to what our much wiser ancestors already know.

Unfortunately, it appears as if most of these compounding pharmacies may not be around for too much longer.

How Are Compounding Pharmacies Being Targeted?

To really get a clear picture of why compounding pharmacies are in jeopardy right now, it is important to understand the two types that exist:

503A Compounding Pharmacies

  • those that compound according to prescriptions specific to particular patients and are required by state boards of pharmacy to comply with USP and other guidelines”
  • “limited to dispensing only for home use and are not allowed to compound large batches, an ability that can lead to lower product costs.”

503B Compounding Pharmacies

  •  those with outsourcing facilities that may manufacture large batches with or without prescriptions to be sold to healthcare facilities for office use only.”
  • allowed to use larger batches to lower their manufacturing costs, passing the savings onto consumers”
  • “held to higher regulatory standards…These facilities are required to maintain full compliance with current good manufacturing practices (CGMP).”

As you can deduce from reading the descriptions above, the 503B pharmacies are the ones who would be synthesizing “grey market” peptides.

(FYI – “grey market” refers to a market in which products are distributed through unauthorized channels that do not belong to the original manufacturer)

If a doctor writes a script for a research chemical and then has a compounding pharmacy make it for the patient (assuming it was done under good judgment), the rules are technically being followed.

Now, this is where things get a little tricky.

When you only have a few 503B pharmacies that are operating under the radar without making too much noise, you won’t see the FDA hammering down on them quickly.

As the old saying goes, “We’ve got bigger fish to fry.”

But when too many people become aware of something that could disrupt the establishment, it’s going to get shut down in the blink of an eye.

For instance, if people purposely 10x their dose of a peptide thinking that 10x dose is automatically better, and then the consequent side effects gain enough volume, the FDA is going to take swift action and restrict access to said peptide.

In a weird way, the majority of the human population realistically needs the “mommy/daddy” FDA figure to tell them what to do and how to do it.

So now we have the 30,000-foot view of what happens, but let’s dive in deeper.

How Does The FDA Drug Approval Process Work?

Understanding the onslaught against therapeutic peptides requires you to know how the FDA approves drugs to be marketed and prescribed.

Here is an infographic taken directly from the FDA website that summarizes the process.

This picture also does a great job of showing just how notoriously difficult it is for a single drug to successfully pass through FDA’s drug approval process:

When you allow drugs that don’t go through the FDA process to mix into the public sphere (without their rigorous standard of testing), you compromise the entire system.

The FDA holds a position that until a particular drug product has been vetted to be safe and effective in their eyes, it should not be given to people.

To be clear, this is separate from prescribing drugs for off-label conditions:

“Off-label” drug use commonly refers to prescribing currently available medication for an indication (disease or symptom) for which it has not received FDA approval.

Off-label use also includes prescribing a drug for a different population or age range than that in which it was clinically tested and using a different dosage or dosage form.

Contrary to what patients might assume, off-label drug use is not the same as experimental or research use. Once a drug is FDA-approved for a specific indication, legally it can be used for any indication.

Off-label prescribing is common; it accounts for 10 to 20 percent of all prescriptions written, although the practice is more common in specific patient populations like children and the elderly.”

Here’s what all of this means:

The ONLY way a doctor can legally (and I do mean 100% legally) prescribe a therapeutic peptide for off-label use to a patient is if the peptide itself is already FDA approved for an existing medical condition.

And when doing so, they would hopefully be operating within the bounds of good medicine and using sound clinical judgment.

From a legal standpoint, it may not be a top priority for the FDA to hunt down doctors who are prescribing unapproved peptides to their patients.

But it would not be classified as a legal action, and one would argue this practice continues to happen due to a lack of enforcement.

The word ‘peptide’ isn’t the issue…it’s whether a drug substance is FDA approved or not.

This would therefore mean that SOME of the stuff made by SOME of the compounding pharmacies are not entirely legitimate (i.e. peptides which are dubbed as ‘research chemicals’).

Such is the nature of the game – you have to play within a closed circuit and follow the rules.

As of this writing, there are less than 500 therapeutic peptides that have been officially approved by the FDA.

The Latest FDA Move That May Be A Death Sentence For Therapeutic Peptides

I informed my private circle of close friends about some horrifying news which would affect therapeutic peptides:

“As some insulin, human growth hormone and other products transition on 23 March from new drug applications (NDAs) to biologics license applications (BLAs), the recently passed government spending bill included a further tweak to add new proteins to the transition.

The NDA to BLA change effectively means that any follow-on products for these NDAs will need to win approval as biosimilars after [March 23, 2020]. The transition was created by the Biologics Price Competition and Innovation Act of 2009, which clarified the statutory authority under which certain protein products will be regulated by amending the definition of a “biological product” to include a “protein (except any chemically synthesized polypeptide).”

For a comprehensive list of the drugs the FDA plans to transition towards being classified as BLAs, go here.

You’ll see a LOT of peptides on that list!

Here is how this announcement affects compounding pharmacies:

“What this means is that pharmacies will no longer be able to compound HCG [human chorionic gonadotropin] without a “Biologics License”.

Conventional pharmacies that compound and dispense medications fall under the 503A pharmacies under the FD&C Act. In short, these 503A pharmacies will not be able to acquire a “Biologics License” and therefore they will not be able to compound HCG.”

We’re not just talking about HCG…mendropins, follicle-simulating hormone, hyaluronidase — every peptide you saw on the FDA list can no longer be compounded into medical formulations.

This is much more than a mere formality.

There are a great deal of similarities between NDAs and BLAs:

The drug is safe and effective for the proposed use and that the benefits outweigh the risks

The labeling is appropriate and contains all necessary information about the drug

Manufacturing methods preserve the drug’s identity, strength, quality, and purity”

However, here is where the difference lies between the two:

“because biological products are processed from living material, BLA content must also demonstrate purity specifically in terms of showing that the final product does not contain extraneous material.

Due to the complexities of manufacturing biological products, a pre-license inspection of the facility is generally required before a BLA is approved. Pre-approval inspections sometimes also take place during an NDA review, but are typically conducted based on risk assessment by the Agency.”

Want to know how expensive an APPLICATION for a BLA is?

As of 2017, the fee is $234,495 ($58,624 if you are a small business).

And a REVIEW of your BLA would set you back another $4569.90.

In total, you’re burning through millions of dollars in program fees, application fees, and the money needed to generate enough clinical data.

Which leads to how FDA generates its operating revenue: 80% from prescription drug program fees and 20% from application fees.

Fortunately, any peptides previously approved as an NDA before March 23, 2020 will eventually be approved as an BLA.

But what about the newer peptides?

What this act does is turn the entire therapeutic peptide industry into one that is too unsustainable for any form of financial success.

And since some compounding pharmacies conduct 50-75% of their business through these peptides, you’re basically putting them out of business.

The only feasible way out would be to have your peptide of choice examined under a study which is monitored and approved by an Institutional Review Board (IRB):

“an IRB is an appropriately constituted group that has been formally designated to review and monitor biomedical research involving human subjects.

In accordance with FDA regulations, an IRB has the authority to approve, require modifications in (to secure approval), or disapprove research.

This group review serves an important role in the protection of the rights and welfare of human research subjects.”

But getting approval from an IRB involves an inhuman amount of complex legal paperwork, not to mention the several thousands of dollars in fees you have to pay PER peptide!

For a single doctor’s office, it’s just not worth the effort, and even the larger companies will not want to touch the IRB application.

Keep in mind that many tip-of-the-spear peptide physicians are not doing this to get rich.

The picture only gets darker from here…

The Biggest Flaw In The FDA Drug Approval Process

So it’s obvious by now that the FDA is the “eye of Sauron” when it comes to determining what does and doesn’t get on the legal drug market.

Where you would be wrong is assuming their entire process is totally legitimate.

The best way to demonstrate this would be through the lab mice being used to conduct animal testing for drugs, which is done long before any human trials are conducted:

I highly recommend you watch the entire video, but here’s a brief summary…

Laboratories have an incentive to breed mice that grow as fast as possible.

More grown mice means more breeding can happen much sooner, which leads to the production of more mice than can be sold off for a hands profit.

Sounds like a perfectly economical thing for a business to pursue, right?

You bet it is — we now know that the United States were not using wild mice for their study, but lab-bred mice which came almost entirely from one source: Jackson Laboratory.

In other words, we are not using mice in their natural habitat, where they are surrounded by hungry predators looking for a good meal.

Here’s where this practice becomes a big deal…

This kind of breeding process favors mice who develop the fastest, and these same mice tend to have abnormally long telomeres.

Telomeres are small DNA sequences located at the ends of your chromosomes and allow your cells to divide in a way where important DNA sequences are retained.

(I’m drastically oversimplifying the science here, but the concept is equally valid)

With each division, the telomeres get shorter, and eventually they become too short to the point where the cells stop dividing and reach a state of senescence.

Studies show that mice with super-long telomeres tend to live much longer, have superior metabolic health and are on average much leaner.

Here’s another important part of this process you need to know about…

The length of these telomeres is maintained through the action of an enzyme called telomerase.

Once telomerase is inactivated, that’s when you get cellular senescence.

Telomerase is present in very high concentrations within cancer cells, which explains why they can divide and replicate themselves so aggressively.

This is also the same reason why these mice, despite living longer, eventually contract cancer and die from it.

This was proven in 2002 by scientist Bret Weinstein when he published the “reverse-capacity hypothesis”:

“…the telomeric differences between humans and laboratory mice have led scientists to underestimate the risks new drugs pose to humans in the form of heart disease, liver dysfunction, and related organ failure”

Here was the conclusion he wrote in the original paper:

“…captive-rodent breeding protocols, designed to increase reproductive output, simultaneously exert strong selection against reproductive senescence and virtually eliminate selection that would otherwise favor tumor suppression.

With their telomeric failsafe effectively disabled, these animals are unreliable models of normal senescence and tumor formation.

Safety tests employing these animals likely overestimate cancer risks and underestimate tissue damage and consequent accelerated senescence.”

These same mice are being liberally used in an endless number of scientific studies, which means that drugs which have no business getting approved receive the green light:

Longer telomeres delay negative drug side effects. As lab mice are frequently used for drug testing, this could potentially lead to the approval of unsafe drugs.”

“All of the science that’s stacked on these mice that’s contingent on their function relative to their telomeres is all compromised”

So what have in essence are “Wolverine-like” mice that can heal exceptionally well.

As a hypothetical example, if you were to investigate a drug for its potential to damage heart muscle in these mice, the results generated would be abnormal in nature.

These lab mice are NOT representative of what could happen, as they can regenerate heart tissue far better and faster than wild mice.

Does this mean a very large portion of the scientific studies done in the past few decades are invalid and therefore irreproducible?

We don’t know, but some people believe it does:

“We try to control everything we can possibly think of, and as a result we learn absolutely nothing.

Garner argues that research based on mice would be more reliable if it were set up more like experiments in humans — recognizing that variation is inevitable, and designing to embrace it rather than ignore it.

using animals as models of disease is a big reason that many results in biomedical research aren’t readily reproducible.”

Perhaps this finding invalidates certain types of studies, while others are still legitimate.

But until we can acknowledge this, comprehensively prove it and make changes to address the issue, there is no definitive way to know.

Examples Of Therapeutic Peptides That Are Superior To Conventional Medical Approaches

There are two reasons I can think of for any desire to ban therapeutic peptides from getting in the hands of everyday people.

  1. Either they are so incredibly dangerous to the point where they can’t be used productively, or
  2. They are so insanely effective to the point where they can hurt the profits made by existing medical treatments that are inferior in nature.

I’m betting on the latter, and I’ll show you why with some concrete examples.

Sermorelin

Sermorelin used to be one of the most effective peptides used by age management physicians to treat growth hormone deficiency in adults.

Multiple compounding pharmacies were making this peptide and it was very affordable for patients to use.

Sermorelin was thought to be superior to ordinary human growth hormone (HGH) injections that attempted to merely replace a lack of HGH in the body through exogenous administration.

Unlike these injections, Sermorelin acts by helping the body naturally secrete more HGH and release to parts of the body where it is most needed.

This happens because its effect is identical to Growth Hormone-Releasing Hormone, which stimulates the pituitary gland to increase HGH production.

On top of being safer and carrying a far lower risk for side effects, it also provided numerous health benefits (this list is just a very small sample):

“Sermorelin enhances the Pituitary Gland’s natural ability to produce endogenous Human Growth Hormone, leading to a more natural Hormone Profile

Sermorelin optimizes the human body, increasing physical and mental performance

Sermorelin strengthens immune health

Sermorelin boosts the liver’s production of Insulin-Like Growth Factor One

Sermorelin helps patients sleep longer, deeper, and better”

However, its production was sadly discontinued in 2008 due to difficulties in the manufacturing process of the active ingredient used to produce commercially supplied sermorelin but not due to safety issues.

And Sermorelin is listed as a banned substance in sports organizations such as WADA and USADA for its anabolic effects, which likely incentivized its discontinuation.

Granted, there are several other HGH-producing peptides that have come into existence and demonstrated favorable results.

But you have to wonder why such an effective biomolecule was suddenly made unavailable1

Cerebrolysin

Cerebrolysin is one of the peptides I plan to feature in my upcoming book about using therapeutic peptides to achieve optimal health.

On top of helping with mild to moderate cognitive impairment, it works phenomenally in helping people recover from traumatic brain injury.

There are HUNDREDS of papers written about Cerebrolysin and its benefits for those people with neurodegenerative disease.

Unfortunately, its newfound classification as a biologic means you won’t be able to get it from any compounding pharmacy, nor will it be available in the US.

Which means you’ll have to use it in other countries if you want to go the legal route:

“Cerebrolysin is currently approved for use in 44 countries as a treatment for dementia and stroke and is in Phase III trials in multiple countries in Europe

While Cerebrolysin is approved for use in Austria, China, Germany, Russia and South Korea, the FDA has yet to approve it for use in the United States”

If you look at Cerebrolysin’s page on the FDA website, you’ll see that it couldn’t even get approval as an orphan drug!

Tesamorelin

Tesamorelin is a different beast as it is technically FDA-approved.

Specifically, its brand name is Egrifta and it was approved in 2010 for HIV-positive patients with lipodystrophy (i.e. a condition where the body has excessive abdominal fat due to its inability to properly utilize and store fat tissue).

This indication came about because lipodystrophy was one of the major side effects that came with using highly active antiretroviral therapy (HAART) drugs.

But as I wrote in Living A Fully Optimized Life, Tesamorelin is THE BEST peptide for fat loss…especially when combined with a fasting protocol such as Metabolic Blowtorch Diet or Guaranteed Shredded).

It can also lower your blood triglycerides and improve cognition.

Of course, all of these additional uses I mentioned are off-label.

Imagine how many millions of people would benefit from the regular use of Tesamorelin, and yet it is limited to an extremely narrow use.

But think of the health insurance companies – they can cover the drug and make a lot of money doing so.

It’s just the way the system is set up: People in the pharmaceutical industry are there to make more money, pure and simple.

A great way to profit off a peptide without having it interfere with the billion-dollar revenue streams generated by other prescription drugs!

BPC-157

I have written prolifically about BPC-157 in a prior blog post that talked about its amazing healing and acceleration recovery properties.

And it’s important here because I want to expand upon what I talked about with Tesamorelin.

Big Pharma will only push to approve peptides if there is an observed economic demand, and if fulfilling this demand makes financial sense.

Put another way, they WILL NOT bring anything to the market that will negatively impact another revenue stream.

Let’s look at this through two hypothetical yet perfectly realistic examples.

The orthopedics industry amassed a global revenue of $51 billion in 2018, with the top dog being Stryker at $13.6 billion in revenue for the year.

There is an ungodly amount of money to be made from medical devices and surgical equipment such as cervical plates, bone screws, implants, and the list goes on forever.

And what are all these things designed to do?

The EXACT same thing that BPC-157 can treat:

“Orthopedic surgery focuses on the diagnosis, treatment, rehabilitation and prevention of diseases of the bones, joints, ligament, muscles, tendons and nerves”

If BPC-157 ever reached mainstream statis, at least 10-15% of the market would be lost.

This is a massive hit, and the industry wouldn’t like it if some tiny little peptide took their precious billions away from them.

The would either pigeonhole the peptide altogether, or find a way to make money from it without blowing up the products and devices which continue to make them money.

It goes deeper, because even the surgeons stand to benefit.

What medical schools often do is work closely with device manufacturers.

The manufacturers invite doctors for a free demonstration which shows them how to use their devices on patients (using human cadavers as demo objects).

Both sides benefit from this arrangement: Doctors get trained, and the manufacturer gets their products bought and used (along with their name on the building).

What do you think would happen if the surgeons suddenly turned around and said, “Don’t bother with surgery, just use BPC-157 for a few weeks and you’ll be fine”?

I’ll let you answer that question for yourself.

Another area where BPC-157 faces great sabotage is in the area of gastrointestinal (GI) health.

BPC-157 has been repeatedly shown to confer multiple benefits for gut-related conditions such as inflammatory bowel disease and stomach ulcers.

On the other hand, you have the purple pill known as “Nexium” for treating acid reflux, stomach ulcers, and heartburn.

This pharmaceutical wonder brought in $1.48 billion for AstraZeneca in 2019, and made $5.22 billion at its peak in 2007.

As a proton pump inhibitor (PPI), it works by inhibiting the release of hydrochloric acid into the stomach.

But when used at higher dosages for too long, it can lead to some serious problems:

“Proton Pump Inhibitors (PPIs) including Nexium and its “parent” drug, Prilosec, have also been shown to increase the risk of heart attack, bone fracture and hypomagnesemia or low magnesium levels.

PPIs are also suspected of causing other serious conditions such as acute kidney injury. birth defects, and acquired infections.

Multiple lawsuits have been filed against the manufacturer of Nexium and many more are expected.”

You have to keep on taking the drug to TREAT the problem instead of FIXING it.

Why on earth would a pharmaceutical company want to kill off such a profitable drug with a peptide that is much more effective, actually addresses the root cause and has virtually no side effects?

Peptides Will Never Compete With Medically Profitable Revenue Streams

Therapeutic peptides, whether natural or synthetic, are backed by an ever-increasing body of medical research which only confirms how effective and safe they are.

People have a better quality of life and have better long-term results when using them.

Plus, many health optimization doctors have successfully used them for decades with their patients.

They are simultaneously a dream come true for mankind and the worst possible nightmare for any pharmaceutical industry.

With everything I’ve told you, let’s recap what companies will do to keep peptides away from public recognition.

You take a therapeutic peptide with widespread potential for treating multiple conditions and have it approved for targeting a very rare and/or undiscovered condition.

Once you get the stamp of approval from the FDA, you charge a shitload of money for it.

You add an additional source of income without jeopardizing the revenue streams you have already built.

Should you catch someone frequently using the peptide off-label (i.e. what it was really meant for), you can have your attorneys go after them and make their lives as miserable as possible.

But how do you track when and why your drug is being used?

Through something called a prescription drug monitoring program (PDMP), otherwise known as a prescription monitoring program (PMP).

Here’s a brief description of how these programs work:

“…[they are] state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, as the individual states deem appropriate, other potentially addictive or abusable prescription drugs.”

A PMP allows you to track all of the drugs being used, who is prescribing them, the person they’re prescribed to, the indication they’re used for, and everything else you could want to know about how your drug is being distributed.

Realistically, the alarms won’t sound if you see just a handful of doctors using a competitive peptide off-label.

But beyond that, it’s time to have a “quiet” conversation with the guilty doctors.

You legally intimidate them, pressuring them to stop using the peptide for off-label purposes or else the peptide will no longer be supplied to their pharmacy.

If you don’t want to be the bully yourself, you can call the FDA!

You just ring them up and say “We saw these doctors using the peptide for conditions not approved for with our drug, and based on our data we do not approve of this.”

The FDA calls those doctors and asks them why the drug is being prescribed for an ailment which is not recommended by the manufacturer.

I could go on, but there are many different ways to exert a lot of pressure on doctors who dare to deviate from the sick care model of healthcare.

This is not the “grand conspiracy theory” many health researchers believe it is, but pure economics and psychology in action.

It’s a natural feedback loop in which people will do whatever it takes to make as much money as possible in the free market society, even if that means suppressing a superior solution.

Most of humanity is sadly asleep and low conscious — they are not going to push back and fight against a system they are unconsciously dependent on.

How The FDA’s Efforts Will Create A Black Market For Therapeutic Peptides

So with therapeutic peptides out of the picture, where else are people going to get them?

As with any drug that becomes illegal, you are going to see a grey market – and possibly a black market – created for these peptides.

Grey goods are legitimate goods that come from the correct manufacturer, but they are sold through unauthorized channels. While these are not illegal goods, it is important to be wary of them. Sellers who use the grey market will usually sell products that have been improperly discarded due to damage or product recall.”

Black market goods are items that are illegal to manufacture or sell. Some black market goods are counterfeit, and some are genuine products that are simply illegal to own or distribute. These are usually a part of a separate, more obscure market than grey goods.”

Without any form of regulation, malicious sellers can get away with selling over-priced peptides that are impure and contaminated:

“As a result, the final price on gray market–traded drugs may be as much as hundreds of times higher than the price that the manufacturer originally received for the product.

Also, as the drugs bounce along the extended supply chain, they may be improperly repackaged, re-labeled, and possibly stored under unsuitable conditions, as well as replaced by counterfeits, compromising their integrity and safety.”

Combine this with the lack of knowledge from the consumer and you have a recipe for disaster.

Think about it: The average person does not know how to properly inject themselves or handle peptides properly!

My prediction is not far removed from reality, as this is already happening with prescription drugs today:

“Due to drug shortages, 52 percent of hospital supply chain employees and pharmacists have been forced to buy drugs from the “gray market,” according to ISMP research.

The gray market consists of drug suppliers that are somehow able to obtain supplies of scarce drugs and sell them at exorbitant costs, sometimes with mark-ups as high as 650 percent, according to previous studies.”

This is the reality we will soon face unless massive and immediate action is taken.

But there’s just one more hurdle we have to deal with…

We Have VERY Few Physicians Who Can Competently Prescribe Peptides

When you do a head count of all the physicians who are certified and well-trained to safely administer therapeutic peptides, you’re talking about a couple hundred at best.

This is an extremely niche area of medicine which requires extensive training and knowledge you won’t get in 4 years of medical school.

And there are very few highly-accredited teaching bodies in existence:

The few peptide physicians in existence have had to put a significant amount of time and money towards obtaining their fellowship training in peptide therapy.

They have the first-hand experience, the connections to legitimate compounding pharmacies, and the testimonies from thousands of patients who can attest to both their doctors and the life-changing benefits of therapeutic peptides.

But without the FDA allowing the use these peptides, these doctors will not have the tools necessary to properly care for their patients.

What You Can Do To Save The Future Of Therapeutic Peptides

We need to collectively come together and do everything we can to stop the FDA from suppressing the use of therapeutic peptides altogether.

So here are some action steps you can take immediately to do your part and have your voice heard.

First, go to SavePeptides.org and tell the world how therapeutic peptides have changed your life for the better.

Every single submission matters, so spare no details in telling the world why we MUST keep these miraculous compounds available for human use.

Staying on the sidelines with off-label use is no longer acceptable!

Second, you can contact the FDA and explain why banning therapeutic peptides will negatively impact the lives of tens of thousands of people.

This website provides you with a good starting template if you need assistance with writing a thoughtful reply.

Third, you always have the option of getting your peptide of choice approved through the IRB process.

This is not a perfect approach and it is extremely expensive and time-consuming.

But if this actually works in your favor, you can have a reputable compounding pharmacy make the peptide for your intended purpose.

Fourth, make sure you support the organizations that work tirelessly to keep the clinical use of peptides alive and running.

All the organizations I listed in the previous section are doing tremendous work in advancing the scientific research of peptides, both old and new.

Just because peptides are currently unapproved by the FDA or used off-label DOES NOT mean that they are inherently unsafe!

Fifth, and finally, share the videos and podcasts I have released on the subject of therapeutic peptides.

The more people know about what therapeutic peptides can do, the better society will be.

This Podcast is the BEST EVER DONE on understanding how to use therapeutic peptides for nearly every conceivable clinical indication.

(CLICK HERE to get the full transcript of this podcast)

And as always…

If you want access to the world’s best health optimization intel before anybody else finds out about it, subscribe to my email list!

The Best Types Of Vitamin C For Fighting COVID-19 Infections

Three weeks ago, I first mentioned the use of Vitamin C for COVID-19 with the help of Dr. Kenneth Wilgers.

Thanks to the brilliant health researcher Doris Loh, we now have a complete understanding of how Vitamin C fights acute respiratory distress syndrome (ARDS) and thereby treats COVID-19.

After the profound live stream we did together, I published an important article revealing a must-have protocol for fighting severe COVID-19 infections with ascorbic acid.

(Both articles contain links to all of Doris’s important research with all the scientific justification necessary to support our recommendations)

Vitamin C Protocols to Stop Covid-19

This article is a strategic deep dive into the specific forms of ascorbic acid (a.k.a. Vitamin C) you should be using and stocking up on to fight the bio-weapon known as Covid-19.

But first, I want to dispel some widely held myths about Vitamin C supplementation.

Why You CANNOT Get Enough Vitamin C From Whole Foods

 

If you read the protocol listed above, the answer should be obvious.

If you’re suffering a severe Covid-19 infection and require two grams of ascorbic acid every 30 minutes for a total of four hours.

Adding in the initial loading dose of 3-5 grams, you’re looking at 19-21 grams total (assuming your symptoms improve within 3-4 hours)

For the sake of the exercise, suppose you got your hands on food with the highest amount of Vitamin C per serving.

This would be the Kakadu plum, with 481 mg of Vitamin C per plum — but let’s be generous and round up to 500 mg.

You would need to eat 38-42 plums in FOUR HOURS just to follow the protocol!

With the type and quantity of ascorbic acid needed to fight COVID-19 and fuel all the required bodily reactions to overcome systemic depletion, foods just won’t do it.

Let’s not forget the amount of fructose you would be consuming, which would cause an inflammatory insulin response depending on your body composition and genetics.

If you are getting a maintenance dose of ascorbic acid while healthy(not experiencing symptoms), there’s nothing wrong with getting your Vitamin C from whole foods (Although realistically, it would still be tough to hit maintenance dosage with citrus fruits and you’d be consuming a lot of fructose).

Vitamin C IS Ascorbic Acid!

By far, the biggest myth worth debunking is that ascorbic acid and Vitamin C are entirely separate things.

This is an agenda pushed by people who are trying to sell “Whole Food” Vitamin C supplements.

Their logic goes something like this:

“Ascorbic acid is an isolate, a fraction, a distillate of naturally occurring vitamin C. In addition, mineral co-factors must be available in proper amounts.

If any of these parts are missing, there is no vitamin C and therefore, no vitamin activity.”

These same people will show you the following diagram to illustrate their point:

Doris Loh does a beautiful job of debunking this notion in one of her posts on the EvolutaMente Forum:

“The proponents of this idea believe that vitamin C is a complex consisting of 5 ‘circles’.

The elements within those 5 ‘circles’ may include ascorbic acid, ascorbigen, factor J and factor P; as well as Tyrosinase & copper.

Sometimes you will see rutin listed together with ascorbigen, and factor K and choline listed together with factors J & P.

…Contrary to what most people believe, the molecular structure between synthetic ascorbic acid, and ascorbic acid made naturally in plants and animals are identical.

In standard scientific literature, this imaginary 5 ‘circle’ Whole Food C complex does not exist.

The individual elements, all except factor J, have clearly identified roles in biochemistry, and their biological functions are quite different in plants and animals.”

(I strongly recommend reading the entire post, which investigates the supposed science behind these false claims)

If you look at any study describing how plants and animals make ascorbic acid, they are referring to Vitamin C.

All of this is a long way of saying that ascorbic acid and Vitamin C are the EXACT same thing!

And don’t be fooled by people who try to tell you there are differences between “natural” and “synthetic” ascorbic acid.

Studies have consistently shown they are identical, both in bioavailability and biological activity.

The Only 3 Types Of Ascorbic Acid You Need

If you are using Vitamin C to treat a COVID-19 infection, it is extremely important to select the RIGHT type of Vitamin C.

You also want to avoid any mainstream disinformation outlet who convinces you to avoid using Vitamin C through fear-inducing propaganda:

“A new report from Yonder, a company that dissects popular social media interactions to understand trends, has found that stalwart anti-vaxxers are pushing a narrative that vitamin C can prevent COVID-19.

There is currently no evidence that vitamin C is a treatment or cure for the coronavirus.”

In fact, there are numerous mainstream physicians, researchers and thought leaders advocating the usage of Vitamin C to treat COVID-19 including:

I also received an amazing testimonial from someone who has personally had great success with using Vitamin C:

“Within 4-5 days the 2 guys with the strict protocol of oral Ascorbic Acid diminished all the symptoms to a very light cough. Within 7 days, no cough and brought the Asorbic down to 6-8k grams daily. 

The guy that did the same IV treatment but didn’t want to take the oral, because he’s a hard head, still has the dry cough and had a big episode of cough and light chest pain 2 days after he stopped the IV.

So the Asorbic protocol works and stops the Covid dead on its tracks, i know it, and also protects you if you dont have symptoms.

I have distributed Vit C to around 30 people including family, employees, and friends and i see the wonders it does.”

With so many influential people advocating Vitamin C, anyone dismissing it with statements like “it’s not scientifically proven” or “where are the studies” are only part of the problem and offer nothing toward the solution.

Dismiss such low vibration humans with extreme prejudice and remember those who are contributing to solving the Covid-19 crisis.

Vitamin C in pure ascorbic acid form orally and for severe infections, a combination of oral and IV Sodium Ascorbate is proven to work.

Here are the 3 types of Vitamin C you should have on deck for treating COVID-19:

Pure Ascorbic Acid Powder

This is the best form of ascorbic acid out of the three.

It will be instantly absorbed by the body and fast assimilation will ensure super-saturation of your red blood cells.

High dose ascorbic acid is critically important for proper immune function as it shuts down cytokine storms while enhancing the supply of blood oxygen (via formation of nitric oxide) when COVID-19  is attacking the heme in red blood cells.

Absorption of high quantities of ascorbic acid is done through sodium-dependent vitamin C transporters 1 and 2 (SVCT1 and SVCT2).

Both of these transporters depend on an electrochemical gradient of sodium for the absorption to take place.

To oversimplify the biochemistry, you need two sodium ions to transport a single molecule of ascorbic acid.

This is specific to ascorbic acid, which is why any buffered form (calcium ascorbate, potassium ascorbate, etc.) will not work.

You MUST use pure ascorbic acid as it is the only form fulfilling its role in the redox reactions while being continuously recycled and replenished.

However, there are two exceptions to this rule…

  1. First, if you are on a low-sodium diet, you may have some difficulty with maximally absorbing pure ascorbic acid. In this case, taking a tiny pinch of sea salt with every other dose of ascorbic acid should be sufficient. Individuals who consume normal or higher levels of sodium in their daily diet will not need it (just be very careful if you have hypertension).
  2. Second, people with stomach issues (i.e. not enough stomach acidity) may require a buffered form.

An alternative would be to consume ascorbic acid with an acidic beverage — or anything that will increase stomach acidity.

Doris Loh personally recommends this brand of ascorbic acid for people who are fighting any level of COVID-19 infection.

Liposomal Vitamin C

Liposomal Vitamin C is the next best version of ascorbic acid.

For those who struggle to absorb pure ascorbic acid, this is a better option as it is absorbed lower in the gut and slows ascorbic acid uptake (due to its buffered design).

*If you choose Liposomal Vitamin C, make sure it contains ascorbic acid and NOT sodium ascorbate.*

It does not exist frequently, so make sure you find a reliable supplier.

This comprehensive guide will tell you everything you need to know about picking and using the highest-quality Liposomal Vitamin C.

Sodium Ascorbate

Sodium ascorbate would be best used in an intravenous (IV) transfusion(drip), especially if it is part of a double-pronged approach that involves oral ascorbic acid.

It helps prevent the formation of cell-free hemoglobin, thereby reducing lung damage and systemic inflammation.

Outside of this specific use, there is no reason to use this as a substitute for pure ascorbic acid.

What You MUST Know About Buying Ascorbic Acid

 

Right now, 99% of the world’s supply of ascorbic acid is made in China.

Doris Loh talked about this in detail on a Facebook post she made in late February:

“50 million grams [i.e. 50 TONNES]. That is how much vitamin C was sent to Wuhan to help their citizens fight COVID-19 on Feb 2nd, 2020.

This is taken from a TWEET by DSM, major manufacture of ascorbic acid in Jiangshan China.

Royal DSM, is a global science-based company in Nutrition, Health and Sustainable Living that has established a state-of-the-art manufacturing site in Jiangshan.

DSM is the same company that produces high quality ascorbic acid known as Quali-C in Scotland.

According to a trusted professional source, the products from China is of the same quality, but cannot be called ‘Quali-C” due to trade-mark rights”

The differentiating factor is the quality control upheld by each manufacturer.

Even if you choose the same manufacturer, you cannot consistently expect the same level of quality.

Your best bet is to rely on the importer and the retailer who conduct quality control studies to verify the purity of each ascorbic acid shipment.

Therefore, you should source your ascorbic acid from a larger and more reputable company who has the money and manpower to enforce stricter quality control standards.

Outside of this, they are all the same.

Ascorbic acid is the easiest natural supplement to make and the cheapest for consumers to buy.

As long as you source it correctly, you won’t go wrong!

My Recommended Sources For Buying Ascorbic Acid

 

I’m currently working with my Aseir Custom business partner Nick Andrews on having my own specific pure ascorbic acid products to help people get massive quantities of pure ascorbic acid at an affordable cost.

In the meantime, here are your next best choices for buying ascorbic acid in a red-hot market.

Evolution Botanicals is offering Liposomal Vitamin C in bulk, alongside Chaga Extract.

And if you need a superior buffered form of ascorbic acid(due to one of the reasons listed above) in high dose containers, I recommend buying BioActive C.

In the near future, Doris Loh, myself and Dr Kenneth Wilgers will be doing another Live Stream on Vitamin C with Doris’s new and yet to be revealed research.

Stay tuned!

Doris-Loh-Jay-Campbell-LiveStream

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Remember:  Raise Your Vibration to Optimize Your Love Creation!

How Hyperbaric Oxygen Therapy Restores Optimal Health In Your Body

Hyperbaric oxygen therapy (HBOT) is rapidly emerging as a much-needed medical alternative for traditional treatments:

“…the [list of conditions approved for HBOT] also includes osteomyelitis, sudden hearing loss, burns, severe anemia, carbon monoxide poisoning, decompression sickness, necrotizing soft tissue infections, crush injuries and arterial gas emboli.

In the majority of these conditions, hyperbaric oxygen is utilized as an adjunct to mainstream treatment. In the case of chronic wounds, this includes debridement, infection control, specialized dressings and offloading.”

Research estimates the HBOT market will be worth $3.91 billion by 2025, with 30,000 treatments performed per year.

This begs the question of why HBOT is becoming the latest interest of biohackers around the world.

In order to provide a complete answer, we must first understand why oxygen carries such great importance for fully optimized health.

Why Is Oxygen So Essential For Human Health

Oxygen is the most important substance for proper bodily function and survival.

We take roughly 23,000 breaths per day without consciously thinking about it.

Even though oxygen being essential for providing our cells with energy, it is one of the most overlooked and under-utilized nutrients.

(FYI: Oxygen is technically a nutrient as it provides nourishment that is essential for growth and the maintenance of life)

We can live for 3 weeks without food, 3 days without water, but only 3 minutes without oxygen:

“Between 30-180 seconds of oxygen deprivation, you may lose consciousness.

At the one-minute mark, brain cells begin dying.

At three minutes, neurons suffer more extensive damage, and lasting brain damage becomes more likely.

At five minutes, death becomes imminent.”

And it turns out we are living in the most oxygen-deficient atmosphere in history:

“Compared to prehistoric times, the level of oxygen in the earth’s atmosphere has declined by over a third and in polluted cities the decline may be more than 50%.

This change in the makeup of the air we breathe has potentially serious implications for our health. Indeed, it could ultimately threaten the survival of human life on earth.

Considering this fact, those who are serious about their long-term health should know about the benefits of enhancing their oxygen levels:

“Increasing your oxygenation levels and being fit and healthy has shown to be important for your health as optimum oxygen levels can improve wound healing, vision, mental clarity and intelligence, boost your immune system, help fight cancer cells, reduce stress levels, improve your heart and respiration and help you to lose weight.”

But is there such a thing as “too much” oxygen?

What Is The Optimal Dose Of Oxygen For Better Health?

We can generally divide the dose for any nutrient into 3 ranges:

  • Recommended Daily Amount (RDA): The minimum amount required before we express obvious disease or dysfunction as a result of deficiency.
  • Optimal Range: The amount required to ensure we have enough of the nutrient to fulfill the complex biological processes taking place within our body.
  • Megadose: Certain situations call for much higher doses to help our body overcome a health problem.

When you think about it, virtually all forms of disease and dysfunction can be reduced to either a deficiency or toxicity.

This goes beyond nutrients – the concept applies equally to our emotional resilience and the way we move our bodies.

In order to achieve peak performance health, we need to get rid of anything which sabotages our efforts towards reaching that state.

If we are toxic, we have an excess of something our body needs to get rid of.

If we are deficient, we are missing something our body requires to perform optimally.

Let’s use this understanding to deduce the right amount of oxygen for optimal health…

An oxygen deficiency is known as hypoxia, a condition where the body cannot efficiently absorb or deliver oxygen to our cells.

Hypoxia can either be systemic yet it can also be local to a specific tissue type or organ.

In the case of local hypoxia, it may be result of an injury or chronic inflammation which does not allow the tissue to be properly oxygenated.

Keep in mind that you don’t need to have hypoxia to be oxygen deficient.

It may be the case you have sufficient oxygenation for your daily routine, yet cannot efficiently increase oxygen supply for an activity such as rigorous physical exercise.

In this instance, your body would have an RDA of oxygen.

Since oxygen is a rate-limiting step in each cell’s ability to produce energy, the conclusion appears to be simple:

Increasing your oxygen absorption increases your capacity to heal, detoxify, produce energy and step up your mental and physical capacities for performing at higher levels.

On the other hand, breathing pure oxygen all of the time is equally deadly:

“Our blood has evolved to capture the oxygen we breathe in and bind it safely to the transport molecule called haemoglobin.

If you breathe air with a much higher than normal O2 concentration, the oxygen in the lungs overwhelms the blood’s ability to carry it away.

The result is that free oxygen binds to the surface proteins of the lungs, interferes with the operation of the central nervous system and also attacks the retina.”

So what is the optimal dose of oxygen?

You ideally want 97-100% of your red blood cells to be saturated with oxygen.

But here’s the catch: Are you are standing right now, most of your cells are already saturated with oxygen and can carry a maximum of 1-3% more.

Commonly Used Methods For Increasing Your Oxygenation Levels

It should be evident that simply buying a mask and a tank of oxygen will not make a meaningful difference in your overall health or rate of recovery.

With this said, there are several tools and techniques which can help you become more oxygen-efficient:

  • Breathing more effectively and deeply via techniques such as Wim Hof breathing and holotropic breathing.
  • Eating foods that are rich in iron
  • Increasing your vegetable intake
  • Spending more time outside in sunshine and fresh air
  • Vigorous exercise
  • Drinking more water

However, all of these methods will lead to an insignificant difference.

Without question, the most powerful way to deliver oxygen and enhance oxygenation of your tissues and cells is through hyperbaric oxygen therapy.

What Is Hyperbaric Oxygen Therapy And How Does It Work?

Hyperbaric oxygen therapy (HBOT) is a very straightforward process:

“Hyperbaric oxygen therapy (HBOT) is a medical procedure in which the patient is enclosed in a total body chamber, inhaling 100% pure oxygen (O2) which is not present at normal atmospheric pressure.

HBOT involves the patient breathing in at least five times the oxygen than in normal air, where oxygen is composed of 21% of the total composition and the composition of nitrogen is at 78%.”

Allow me to explain why the first sentence is the most important one in the quoted description.

We need pressure exerted from the atmosphere in order to absorb oxygen.

At sea level, the atmospheric pressure exerted on our bodies at all times is roughly 14.7 psi.

The pressure is sufficient enough for oxygen to flow from an area of higher concentration (the atmosphere) to an area of lower concentration (our lungs).

Here is a simplified diagram which shows how this process of oxygen diffusion works (credit to Dr. Jason Sonners):

Let’s examine this principle in 3 different scenarios:

Oxygen Absorption At High Altitudes

Suppose you are 8,000 feet above sea level, where the atmospheric pressure is reduced.

The pressure of air is 564 mmHg and the pressure of oxygen is 118 mmHg.

Compare that to sea level, where the pressure of air is 760 mmHg and the pressure of oxygen is 159 mmHg (hence why air is ‘thinner’ at higher altitudes).

In this case, you would experience far less oxygen absorption.

Fortunately, your body can “feel” this difference and increase red blood cell production, which in turn improves your body’s ability to efficiently carry oxygen.

This is made possible through hypoxic induction factors (HIFs), which are helps your body adapt as the pressure of oxygen – and oxygen percentages – change.

You can think of them as “oxygen sensors”.

This may not sound like a big deal, but the Nobel Prize in Physiology or Medicine for 2019 was awarded to a group of scientists who discovered how cells sense and adapt to oxygen availability:

“…the response by gene expression to changes in oxygen is directly coupled to oxygen levels in the animal cell, allowing immediate cellular responses to occur to oxygenation through the action of the HIF transcription factor”

Oxygen Absorption Below Sea Level

The phenomenon described for high altitudes works the opposite way in lower altitudes.

As we descend below sea level, the pressure increases and therefore our ability to absorb air and oxygen also increases.

Pretty straightforward, right?

Hyperbaric Environments

Here’s where HBOT sets itself apart from other oxygenation methods.

We can actually control the amount of pressure exerted on a person and the amount of time spent in this pressurized environment.

Therefore, HBOT helps the practitioner predictably control the amount of increased oxygen absorption a patient can take into their cells.

Once absorbed, this “extra” oxygen can be used for making ATP and energy, increasing the capacity for working tissues to perform (or increase the capacity of healing and recovery).

This induces a state called hyperoxia, a state where the body has a greater supply of oxygen than necessary.

The University of Iowa provides a straightforward description of how hyperbaric environments work:

“The high level of oxygen in the blood allows improved oxygen delivery to tissues that are not getting enough oxygen at baseline (i.e. hypoxic tissues). 

Having times of alternating hyperoxia and hypoxia (as occurs during a series of HBO treatments) promotes the growth of new blood vessels into the hypoxic tissues, a process known as neovascularization.

Hyperoxia enhances the body’s ability to kill certain bacteria.”

In other words…

Through by-passing the red blood cells and absorbing oxygen directly into our plasma and tissues while in a chamber, we increases oxygen absorption by 28-40%.

If you want to understand the concepts discussed in greater detail, I highly recommend watching this short primer video on HBOT:

The Most Important Health Benefits Of Hyperbaric Oxygen Therapy

With a full understanding of how HBOT works, the health benefits it provides to patients are fairly obvious.

Even though 120 reported conditions (and counting!) are proven to be effectively treated by HBOT, here are the 5 most important ones:

1) Reduces Incidence Of Disease

HBOT has the ability to improve oxidative metabolism in cells without increasing production of harmful reactive oxygen species.

In turn, this significantly reduces the incidence of lifestyle diseases such as high blood pressure and type 2 diabetes.

2) Heals Wounds

HBOT has the ability to stimulate angiogenesis, which is the process through which new blood vessels are formed.

Angiogenesis is an essential process for healing wounds, as increased blood flow is necessary to provide nutrients and oxygen to the affected tissue.

This same mechanism allows HBOT to be useful for patients suffering from erectile dysfunction!

3) Reduces Inflammation

Another reason why HBOT is so effective at healing soft tissue injuries is due to its anti-inflammatory effects.

This was observed in a cellular study published in Nature where HBOT was able to oxygenate injured muscle and regenerate skeletal muscle.

4) Possesses Anti-Microbial Properties

HBOT can enhance the immune system’s ability to kill harmful micro-organisms, while working synergistically with other antimicrobial agents.

In doing so, HBOT can be used to treat deep and chronic infections and therefore prevent them from expanding.

5) Assists In Fighting Against Cancer

A very comprehensive review of HBOT’s effects in treating malignancies came to the following conclusion:

“We conclude that the administration of [HBOT] can provide many clinical benefits in the treatment of tumours, including management of highly malignant gliomas.

Applied immediately before irradiation, it is safe and well tolerated by patients, causing rare and limited side effects.

…[HBOT] can also increase the cytostatic effect of certain drugs, which may render standard chemotherapy more effective.”

In particular, HBOT is effective due to its ability to treat areas of tutors where local hypoxia is taking place.

What You Must Know About Your First Session With Hyperbaric Oxygen Therapy

If you are using HBOT for the very first time, you may have some questions:

  • How many sessions do I need to do?
  • Can I use a soft chamber or a hard chamber, and which one is better?
  • What’s the best HBOT protocol for health optimization?

Each patient is a biochemically unique individual, which means there is no universal answer.

Three variables are manipulated during the treatment: Time spent under pressure, pressure levels used, and oxygen levels the patient is exposed to.

Some conditions will require higher oxygen levels and/or higher pressure levels, such as radiation burns and open wounds.

For other conditions, you will notice the following being used: Frequent and longer sessions, mild pressure levels, and lower oxygen levels.

This is especially true if a soft HBOT chamber is being used in the convenience of your home. ‘

As long as you are not exceeding two hours per session and the chamber pressure is 3 times less than normal atmospheric pressure, side effects of HBOT are mild to non-existent.

How You Can Start Using Hyperbaric Oxygen Therapy At Home

Having used HBOT myself, I fully endorse the practice.

If we want to influence our body to improve recovery, performance and overall quality of life, it is a useful tool in any biohacker’s arsenal.

Whenever I feel run down or find myself suffering from soft tissue pains and strains, HBOT helps me rapidly recover and heal.

And if you want to use an in-home HBOT chamber to get the benefits of oxygen therapy, look no further than HBOT USA.

This organization is run by Dr. Jason Sonners, one of the world’s leading HBOT doctors and the author of Oxygen Under Pressure.

When you sign up to receive one of his high-end HBOT machines, you will receive two things:

  • A generous discount exclusive to my subscribers
  • An in-depth consultation to see what your issues are, your health goals, and the protocol that’s both safe and effective for your circumstances.

Be warned: These chambers are a significant financial investment.

Unless you are absolutely serious about your health and optimizing every single facet of your life, you will not experience the full extent of the benefits provided by HBOT.

But if you are fully committed to high-performance health, however, then HBOT USA’s chambers are right for you.

When you’re ready to start using HBOT, you can sign up and get my discount by clicking here.

And as always…

If you want access to the world’s best health optimization intel before anybody else finds out about it, subscribe to my email list!

How To Use Vitamin C To Stop COVID-19 & Acute Respiratory Distress Syndrome (ARDS)

The race is on around the world to devise – or repurpose – a treatment to stop coronavirus once and for all.

So far, our options are few and far between.

We can supplement with nutraceuticals such as Chaga Mushroom and Vitamin D, as I had explained in my COVID-19 survival guide.

There’s the pharmaceutical interventions of hydroxychloroquine and azithromycin making waves in the medical field (even though the potential side effects of HCQ leave a lot to be desired).

We also now know that Covid is attacking red blood cells (heme)and starving the cells of oxygen.

Covid-19 Causing Hypoxia

But there’s one beautifully simple vitamin which may hold the answer to fighting COVID-19 infections.

It’s extremely accessible, insanely cheap to manufacture, and there’s literally nothing stopping us from using it.

I’m talking about Vitamin C, also known as Ascorbic Acid.

Why You WILL NOT Hear About Vitamin C From Mainstream Medicine

If you try to do a Google search for “coronavirus and vitamin C”, you’re not going to like what you see.

Reputable health authorities such as Healthline are proactively speaking out against vitamin C before people even have a chance to hear about it:

“With the 2019 coronavirus COVID-19 pandemic, it’s especially important to understand that no supplement, diet, or other lifestyle modification other than social distancing and proper hygiene practices can protect you from COVID-19.”

“High dose IV vitamin C has been used in China to help improve lung function in people with COVID-19. However, vitamin C’s effectiveness is still being tested. There’s no evidence to support the use of oral vitamin C supplements for COVID-19.”

(FYI – I frequently link to Healthline’s articles when I’m writing content, but I really think they missed the mark on this one)

Even the World Health Organization refuses to acknowledge the possibility of Vitamin C treatment, opting to spend its resources on clinical trials for other drugs that may not have the same level of efficacy.

To make a long story short, Big Pharma doesn’t give shit about human health.

Their only concern is making money and profiting off disease through the sale of their expensive drug interventions.

Vitamin C will never be approved by the orthodoxy of Big Pharma as there is no patent opportunity nor financial incentive as Ascorbic Acid is dirt cheap to manufacture.

If you wait for the higher echelons of mainstream media and Big Pharma-owned doctors to offer their stamp of approval”on Vitamin C, it will already be too late.

This is all in spite of early results showing extraordinary promise, such as the ones obtained from Dr. Enqiang Mao in Shanghai:

“..his group treated ~50 cases of moderate to severe cases of COVID-19 infection with high dose intravenous (IV) Vitamin C.

The IV Vitamin C dosing was around 10,000-20,000 mg a day for 7-10 days, with 10,000 mg for moderate cases and 20,000 for more severe cases by the pulmonary status (mostly the oxygenation index) and the coagulation status.

All patients who received IV Vitamin C improved and there was no mortality.

Compared to the average of 30-day hospital stay for all COIVD-19 patients, those patients who received high dose IV Vitamin C had a hospital stay that’s about 3-5 days shorter than the overall patients”

Despite the emerging evidence, some academics are dangerously fighting against Vitamin C supplementation:

“…[Biochemistry professor Peter McCaffery] said that even if IV vitamin C worked to shorten or cure COVID-19, it would likely only be a stop-gap before therapies directed at the virus, such as vaccinations, took over”

Yeah, good luck waiting all the way until next year for a mass-produced vaccine:

“Tests like these are taking place much quicker than would normally be the case, and some are using new approaches to vaccines. It follows that there are no guarantees everything will go smoothly.

But even if these – or any other tests – do prove successful, it’s not expected that manufacturers will be able to produce a mass-produced vaccine until the second half of 2021.”

If people followed the greed of Big Pharma and harmful advice of quack academics by sitting on their hands until 2021 to inject a poorly designed and understood vaccine, millions will likely die.

The Relationship Between SARS-CoV-2 and ARDS

So how exactly does absurdly high doses of Vitamin C (i.e. ascorbic acid) work to stop COVID-19 from doing more damage?

First, let’s review an important concept discussed by Dr. Kenneth D. Wilgers in my most recent article about the coronavirus.

(REMEMBER: SARS-CoV-2 is the virus, COVID-19 is the disease CAUSED by the virus)

One of the main mechanisms of SARS-CoV-2 involves depleting ascorbic acid, which then weakens the immune system and results in acute respiratory distress syndrome (ARDS):

“Acute respiratory distress syndrome (ARDS) occurs when fluid builds up in the tiny, elastic air sacs (alveoli) in your lungs.

The fluid keeps your lungs from filling with enough air, which means less oxygen reaches your bloodstream. This deprives your organs of the oxygen they need to function.”

Sadly, ARDS is the most common outcome in COVID-19 patients:

“Among 201 patients with confirmed COVID-19, 41.8% developed ARDS, and, among these patients, 52.4% died.”

“Certain risk factors, such as older age, were associated with developing ARDS and dying among patients with confirmed COVID-19, most likely due to a weaker immune response”

Look at those numbers…the majority of ARDS patients DO NOT SURVIVE!

The damage done to their lungs is simply too great.

The symptoms of ARDS are absolutely horrific:

  • Difficulty in breathing
  • Low blood oxygen
  • Sepsis
  • Elevated inflammation (i.e. abnormal readings in inflammatory markers), leading to higher rate of organ failure and a greater mortality rate

That’s not the worst part…

EVEN if a patient tests negative for COVID-19, they can still demonstrate abnormal lung damage similar to what ARDS would cause.

Fortunately, a new artificial intelligence algorithm is 70-80% accurate in predicting which COVID-19 patients will develop ARDS based on certain clinical characteristics:

(from most predictive to least predictive)

Mildly elevated alanine aminotransferase (ALT), indicating possible liver toxicity

Presence of myalgia (body ache), likely due to higher oxidative stress

Elevated hemoglobin (red blood cells), due to free hemoglobin floating around in the plasma

Liver injury will definitely lessen the odds of survival, as elevated aspartate aminotransferase (AST) is highly prevalent in severe cases of COVID-19.

The Direct Connection Between Ascorbic Acid And Coronavirus

The connection between SARS-CoV-2 and ARDS is clear, but where does Vitamin C fit into the picture?

Allow me to explain in layman’s terms…

Our body contains special types of white blood cells called macrophages, which are responsible for consuming and destroying harmful organisms and cellular debris.

As you can imagine, they are an essential part of our immune response.

In 2002, a pivotal study done in peritoneal cells of mice (i.e. membrane cells located on a thin layer of tissue within the abdomen) examined how ascorbic acid concentration in the cells change when oxidative stress increases.

Specifically, the study was looking at macrophages and other cells responsible for making our immune system functional:

Just take a look at the bars corresponding to “M” (macrophages).

You would think that macrophages are unable to accumulate ascorbic acid.

Not true — it turns out the macrophages exposed to oxidative stress, can accumulate, recycle and reuse ascorbic acid 100 times faster than they normally would.

These macrophages also use ascorbic acid to generate nitric oxide (known to improve blood flow), which is why ascorbic acid has such low concentrations in macrophages.

However, nitric oxide is also part of the main mechanism through which macrophages kill pathogens, known as “oxidative bursts”.

If macrophages have insufficient nitric oxide, they cannot kill pathogens.

Before I move on to the main point, let me elaborate further on how a lack of endogenous (i.e. produced in the body) nitric oxide production can be dangerous…

(By now, it is obvious why nitric oxide depletion is deadly for COVID-19 patients who also have hypertension)

The real reason why nitric oxide deficiency is so terrible in macrophages is that the same “oxidative burst” is also used to kill monocytes (i.e. their “parent” cells).

When you have too many monocytes, they can differentiate and create more macrophages.

This, in turn, leads to a massive cytokine storm, a.k.a. CHRONIC INFLAMMATION!

4 Reasons Why Vitamin C Can Fight Against COVID-19

From the explanation above, we can deduce several reasons as to why ascorbic acid is vital for fighting COVID-19:

1) Ascorbic acid increases nitric oxide production by regenerating an enzyme called BH4.

BH4 regeneration is essential for synthesizing nitric oxide, and no other molecule in existence can replace ascorbic acid.

2) Ascorbic acid stabilizes free hemoglobin, restoring their ability to carry oxygen.

The “free hemoglobin” mentioned earlier are incapable of carrying oxygen.

This is the REAL reason why people with ARDS are unable to breathe and require intubation. ‘

3) Ascorbic acid is regenerated, recycled, and reused by the body.

Ascorbic acid is known as a “redox” molecule, which means it can take electrons from surrounding biomolecules and give electrons away.

Once it is taken, it can continually reuse itself to help the body produce more nitric oxide.

This was proven by a very recent study which demonstrated that up to 4,000 mg of ascorbic acid taken by mouth can produce the same rapid increase in plasma concentration as an intravenous infusion”:

Notice how the peaks representing oral ascorbic acid easily lead to twice the amount of Vitamin C in the bloodstream compared to IV Vitamin C!

4) Vitamin C has a proven history of fighting respiratory infections

Vitamin C has been examined for the past 100 years for its ability to alleviate common colds.

In addition, scientists suggested its use for treating the 2003 SARS virus when it was at its peak.

The Optimal Vitamin C Dosing Protocol For Combatting COVID-19

Doris Loh, one of the world’s TOP Vitamin C researchers, suggests the following interventional protocols for oral ascorbic acid in adults:

Vitamin C Protocols to Stop Covid-19

For Children:

Vitamin C Protocols to Stop Covid-19-in-Children

I STRONGLY recommend reading both of her articles about the connection between Vitamin C, ARDS and SARS-CoV-2 (here and here).

Please watch the profound live stream I did with her Friday April 3rd that provides the scientific research proving the mechanism of action of Ascorbic Acid in fighting Covid-19 and Acute Respiratory Distress Syndrome (ARDS).

Additionally, I’ve created my own video to recap Doris’s Ascorbic Acid dosing protocols listed above. 

A Comprehensive Collection Of ALL MY COVID-19 Survival Intel

I can’t tell you what the future holds for the coronavirus.

There is NO telling what new intel may come our way.

But there’s only so many links I can add – both to world-class researchers around the world and to my own material.

So here’s a must-have compilation of all my publicly released content about COVID-19.

I recommend following the instructions found in this graphic for the ‘essential nutraceutical’ interventions.

How To (Actually) Understand The Coronavirus’ TRUE Global Impact – a blog post which examines the global implications of the coronavirus.

How My Family and I Used High Dose Vitamin C to Defeat Covid-19 -How One Man and His Family Used High Dose Vitamin C to Defeat Covid

COVID-19 Wiped Me Out For 4 Days – a heartfelt interview with a first responder who contracted the coronavirus and survived

How To Become Immune To COVID-19 – Genius researcher Clif High shares how he anticipated the virus spreading in December 2019 and started taking measures to protect himself.

Understanding Your DNA to Prevent COVID-19 Infection – This broadcast with Mayo Clinic researcher Dr. Anthony Jay reveals certain genetic patterns that may increase one’s susceptibility to COVID-19.

This highly detailed email to my newsletter subscribers “Ask Jay Tuesday: The Cheat Sheet to Defeat Covid-19.

If you want access to the world’s best health optimization intel before anybody else finds out about it, subscribe to my email list!

How To Receive Fully Optimized Health Care During The Coronavirus Pandemic

With stay-at-home lockdowns being ruthlessly enforced across the world, many patients are left wondering if they can receive the healthcare they need.

Unfortunately, the answer isn’t so straightforward.

Many doctors are forced to provide telemedicine options to patients in an effort to keep themselves safe:

“Starting this week, most doctors will talk to patients on the phone, by video conference or through email as a first-step to determine who needs to come to the office for an in-person appointment.”

“…some patients will be told upcoming, non-urgent appointments will be postponed for weeks or months.”

All of this is being done to minimize the amount of contact between healthy people and potential COVID-19 carriers.

And frankly, I foresee this going on for the next 4-6 months at least.

Why Hospital Visits Are A TERRIBLE Idea Right Now

Here’s the truth: EVEN if you were fully capable of seeing your physicians in-person, this could lead to dire consequences for your health.

Healthcare workers all across the country are getting infected with COVID-19 due to their frequent exposure to sick patients:

“The coronavirus pandemic, which has infected more than 30,000 people in New York City, is beginning to take a toll on those who are most needed to combat it: the doctors, nurses and other workers at hospitals and clinics.

In emergency rooms and intensive care units, typically dispassionate medical professionals are feeling panicked as increasing numbers of colleagues get sick.”

This is not a “hoax” – I recently hosted a tell-all interview with an emergency medical responder in his prime who got knocked out by COVID-19 for 7 days straight.

Even people who have minor symptoms and injuries are refusing to go near a hospital, and rightly so.

The absolute best thing anybody can do is to NOT GET THE VIRUS!

But this doesn’t change the fact that millions of people still need access to competent medical professionals who can help them optimize their health.

And if you’re a hormone optimization patient who requires access to your treatment, the situation becomes darker.

So what’s the solution to this?

Why Telemedicine Is The Future Of Healthcare In The 21st Century

Without question, the $40 billion telehealth market is going to exponentially increase after we survive the COVID-19 pandemic.

Just take a look at some of these surprising statistics about telemedicine:

  • 76% of hospitals partially or fully use teleheath, compared to 61% in 2015
  • 39.5% of radiologists use telemedicine to interact with other patients
  • 38.8% of emergency medicine physicians use telemedicine to interact with other providers

And it’s not hard to see why.

There are an endless number of advantages tele-health has over the traditional “sick care” model:

  • Patients can get a response from physicians rapidly, compared to the 18.5 days they would have to wait for an in-clinic visit
  • For every $1 spent on implementing tele-health, the estimated ROI is $3.30
  • Introducing telemedicine into employee wellness programs could save up to $6 billion annually
  • Over 36 million Americans are already using tele-health services

Put another way, tele-health is the future of “done-for-you” healthcare that’s much faster to implement and easier to execute:

“Automatic appointment reminders, stress-free in-app scheduling tools, and remote physician consultations help patients keep up with their healthcare needs over time.

Patients no longer have to cross physical barriers to speak with a healthcare provider, changing the way the average person interacts with and thinks about the healthcare system.”

But what exactly should you be looking for in a tele-health provider?

How can you choose the right one and avoid getting locked into an expensive scam operation?

Use the following questions to vet any telemedicine provider you come across:

  1. Will I have full access to my blood work after it is completed?
  2. How will my blood work be taken (As I explained in The TOT Bible, RUN the opposite direction if they use salivary tests), and how often will it be taken?
  3. How long have you been managing patients on hormone optimization therapy, and how much of your total practice do these patients represent?
  4. Will I be allowed to self-administer my own hormone injections upon receiving a prescription?
  5. What is your cost for an initial consultation, and is there a monthly patient care fee?
  6. Will any of my treatments be covered by my insurance provider?
  7. Can my problems be described to me in a way that is simple and easy to understand?

Fortunately for you, I’ve already done the leg work of finding the best telemedicine provider in the United States.

Why Peak Should Be The ONLY Telemedicine Provider You Work With

Peak is the the easiest and fastest way to receive hormone optimization therapy from the comfort and convenience of your own home.

It was founded by Saad Alam out of his frustrations with the inadequate care he received from mainstream medicine.

Having watched several of his friends contract COVID-19 and end up attached to ventilators, he’s doubled down on his efforts to rapidly expand his telemedicine practice across the USA.

Patients need care RIGHT NOW when it matters most, and that care should not be compromised in the slightest bit when it comes to quality.

Here’s what you get when you sign up with Peak today:

Accessible Healthcare, 365 Days A Year

Have a question for your peak doctor?

They’ll make sure every concern gets answered promptly and with full clarification.

Individualized Treatment From Experiential-Based Physicians

Every Peak physician will take the time to understand:

  • Your health goals
  • Why you are seeking to fully optimize your health
  • How aggressive you want to be with your route of treatment
  • Any side effects you are worried about

Your physician will address different routes of treatment available to you, while also exercising full transparency about their advantages and disadvantages.

You are in the driver’s seat and the doctor is your partner to help create an optimization plan together.

Automatic Shipping Of All Necessary Medicines And Equipment To Your Doorstep

With a plan fully set in motion, you will receive everything you need to fully optimize your health.

Needles, disposal containers, alcohol wipes, blood tests, ancillary medications…it’s all included in the package.

Should you need additional blood work or an in-person consultation, a physician’s assistant or nurse practitioner will be sent directly to your house.

Frequent Follow-Ups To Help You Achieve Extraordinary Health

Peak will automatically send you a testing kit to repeat your blood work every 90 days.

This will ensure you are on track towards better health and vitality.

And if you have any questions or concerns, no problem!

You can schedule an additional consultation with your doctor to answer all of your concerns and adjust your treatment plan where necessary.

The Patient Onboarding Process At Peak

So how does the patient experience with Peak play out, from start to finish?

I’ll reveal how the process works when it comes to your blood work, as this is arguably the most crucial part of hormone optimization therapy…

1) Purchase a test kit from the official Peak website.

2) Once you receive the kit, take the blood test.

It will all be laid out with easy-to-follow instructions.

After fasting for 12 hours, wash your hands in warm water and jump around a little bit.

Wipe your finger with an alcohol wipe and inject yourself with one of the lancets provided in your toolkit.

Allow four drops of blood to be transferred onto a dry blood card from the finger receiving the injection.

3) Send the dry blood card to a certified lab.

Put the dry blood card into a bag, and mail it to the address provided in your test kit.

All laboratories used to give Peak the results of your blood test are CLIA and CAP certified, which means they are fully accredited by official government bodies.

4) Wait for Peak to process the results of your blood test.

Eight specific hormones will be examined in your blood sample:

  • Total testosterone
  • Free testosterone
  • Luteinizing hormone (LSH)
  • Estradiol (E2)
  • Liver function enzymes
  • AST/ALT
  • SHBG
  • Albumin

Anyone who uses therapeutic testosterone knows how essential these 8 biomarkers are for assessing the results of their treatment protocol.

5) Review the results with a board-certified doctor from Peak

You will receive an email notification to schedule a consultation with your physician.

Every doctor who works for Peak has years of experience in working with men to fully optimize their hormone levels.

Using your lab results, you will be recommended the best treatment for your circumstances.

Needle-free applications for therapeutic testosterone are available, including my highly-recommended scrotal testosterone cream.

At every single step of the process, Peak serves a much-needed guide on your health optimization journey.

They will dial your treatment down until you are at your physical and mental peak.

An Exclusive Peak “Special” For My Loyal Readers

In the age of surviving the coronavirus, Peak is fulfilling an essential public service sorely needed by the general public.

A seamless and fully automated process, an at-home blood kit, knowledgeable physicians, comprehensive customer service, medication shipped direct to your door…what’s not to love?

And since you’re reading this article right now, I want to offer you a VERY special deal:

1) Comprehensive Lab Testing & One-Time Physician Consult for $30 (original value of $200)

2) Comprehensive Hormone Optimization Therapy For $149/month (original value of $199/month)

Click this link and you can start taking advantage of one of the world’s most convenient healthcare services in existence.

You will be very hard-pressed to find the highest-quality of healthcare optimization at such low prices anywhere else.

And as always…

If you want access to the world’s best intel on full-spectrum health optimization before it becomes mainstream, join my email list today!

COVID-19: Novel Interventions For A Novel Virus

This article was written by Dr. Kenneth D. Wilgers. All I’ve done is paraphrased what he wrote and condensed it down into the most important information you need to know. 

Everything you will read here is of sound reason and scientific integrity, but none of this information should be considered medical advice. 

This article is meant to help patients in the shortest amount of time, since there are no *official* medically tested interventions as of this writing. 

The Correct Categorization Of The Coronavirus

Before we begin, it’s important to get some facts straight:

  • SARS-CoV is the SARS virus of the 2003 SARS epidemic.
  • SARS-CoV-2 is the current “coronavirus” which is a SARS coronavirus that is closely related to the SARS virus of 2003.
  • COVID-19 is the disease caused by SARS-CoV-2.

As you will see, the novel coronavirus we are observing right now (SARS-CoV-2) is very closely related to the SARS virus (SARS-CoV) that caused the SARS epidemic of 2003.

However, there are some very crucial differences which make the virus – and how it clinically presents itself – unlike anything we’ve ever seen before.

How Is SARS-CoV-2 Transmitted?

There is a reason why SARS-CoV-2 can infect your cells and be transmitted at a far greater rate than the SARS virus of 2003. 

This new virus contains furin cleavage sites on its external spike proteins, whereas the virus of 2003 does not.

Here’s what this means…

These furin cleavage sites interact with furin enzymes on the surface of host cells, thereby gaining access to the cell.

(FYI…Furin is responsible for catalyzing the maturation of biological compounds which are then cleaved to form active proteins in your body)

These furin enzymes are present on every cell line in the human body, which is why SARS-Cov-2 is 1000 times more transmissible than SARS-Cov-2. 

This is also why many infected patients show signs of nervous system dysfunction. 

And if you read my previous article on preparing for the coronavirus outbreak, you know how people with pre-existing diseases are more susceptible to catching the virus and having fatal outcomes. 

Since SARS-CoV-2 gains access to the cell via the angiotensin converting enzyme 2 (ACE2) receptor, some doctors advise patients to stop using drugs which block this receptor. 

When you block the receptor with pharmaceuticals, the cells up-regulate these receptors.

As you can imagine, this increases susceptibility to the virus.

(BTW, this is the same reason why men who use phosphodiesterase 5 inhibitors like Viagra and Cialis find the drug becomes less effective over time) 

Considering how the receptors are found in the lung, kidney and blood vessels, this is why you find the most damage done in those organs.

As always, please consult a licensed healthcare professional about any changes you wish to make to your current medication regime. 

What Happens When SARS-CoV-2 Enters The Cell?

Like any virus, SARS-CoV-2 will “hijack” the components of the host cell so it can replicate itself via the mTOR (mammalian target of rapamycin) enzyme. 

mTOR is primarily responsible for controlling cell growth, and is one of the main reasons why cancer cells grow and replicate far faster than the body can handle. 

SARS-CoV-2 starts replicating until the entire cell is filled to max capacity and it bursts, which releases more copies of the virus to infect other cells. 

For those of you who don’t know, viruses are merely tiny packets of DNA or RNA that can “produce” the proteins needed to build their structure and maintain their function. 

Viruses CANNOT survive without interacting with a host, nor can they replicate without a host. 

The virus then targets specific processes in the cell to trigger an immune response.

While this immune response is healthy when acute (i.e. to try and kill the virus), it is fatal when in excess as it will cause even more damage to the host.

This mechanism of viral infection is very similar to how chronic inflammation acts in the body and becomes the root of many chronic diseases. 

By far, you will see the most damage done by SARS-CoV-2 in the lungs. 

This is why the screening exam for positive cases looks for symptoms such as fever, cough and shortness of breath.

It is also why the majority of deaths caused by SARS-CoV-2 are a result of Adult Respiratory Distress Syndrome (ARDS), a specific type of respiratory failure. 

ARDS develops through the host immune response, and for this reason it becomes incredibly difficult to treat once it has started.

(Source)

The picture above shows how ARDS causes damage to the lungs. 

Chronic inflammation is a very complicated and multifactorial process, but you can already begin to understand how SARS-CoV-2 leads to a very unfavorable outcome in the body. 

The Current Rate Of SARS-CoV-2 Injury Death

(Source)

If you read my article about surviving the coronavirus, the information above is of no surprise to you.’

Older individuals, patients with compromised immune systems, and anybody with pre-existing metabolic is most susceptible to death. 

(Source)

As of March 23, this is where we stand with the OFFICIAL numbers regarding SARS-CoV-2 (of course, the unofficial numbers are probably several magnitudes higher).

 

(Source)

And if you look at the graph above, it is undeniably clear that SARS-CoV-2 is spreading at an exponential rate. 

Proposed Methods For Preventing SARS-CoV-2 And Minimizing Bodily Damage

Health officials and organizations worldwide are scrambling to find new medications and novel uses of existing medications to treat SARS-CoV-2

For example, a recent study was published outlining how a protocol of hydroxychloroquine and azithromycin was effective in a small sample of patients (an antimalarial drug and an antibiotic, respectively).

Another review published in Cell Discovery also discussed how existing pharmaceutical agents can be repurposed for treating SARS-CoV-2. 

What is about to be presented are some thorough research options for preventing infection and/or reducing the degree of injury caused by infection.

NOTE: None of these interventions are endorsed by any medical authority, nor are they recommended by any medical society or advisory board. 

Vitamin C

High doses of Vitamin C (up to 24,000 mg per day) are already being used in China, with several clinical trials (like this one) already being conducted as we speak.

It’s commonly used to treat colds and prevent infections, and has been for several centuries. 

Vitamin C also…

An amazing article from Doris Loh is also an excellent resource on the power of oral vitamin C to combat and stop Covid-19 in it’s tracks.

Jay Campbell made this video on how to dose Vitamin C if one contracts or believes they have initial symptoms of Covid-19.

For the best Vitamin C you can get your hands on, I recommend using Liposomal Vitamin C.

I think it’s safe to say maintenance dosages of C now are anywhere from 1-5gms per day for everyone depending on size and body weight.

Chaga Mushroom

Cliff High now known as the #Chaga_gangsta has been all over the usage of this supplement either in capsule or tea form.

His video’s are about the best on planet earth providing awareness to defeating Covid-19.

This article on the 5 Phases of Covid and their treatment (summarizing Cliff’s work) is also excellent.

Nitric Oxide (NO)

Nitric oxide helps inhibit the production of pro-inflammatory compounds, thereby protecting against ARDS.

I would not recommend the use of pre-workout supplements, as they also contain large amounts of caffeine. 

Foods such as black pepper, pine bark extract, beet root extract, citrulline and arginine can help boost nitric oxide production as well.

Tadalafil at a precise micro-dosage of 2.5-5 mg daily can also increase nitric oxide production.

If you want a supplement specifically engineered to increase production of nitric oxide, NEONOX comes highly recommended.  

Zinc

Zinc has been proven to have beneficial effects for treating cold sores and common colds.

However, it can exhibit antiviral activity against SARS-CoV (SARS 2003), H1N1, HIV, papillomavirus, and many other viruses. 

There are several forms of zinc available as supplements.

I personally recommend zinc gluconate as it gets absorbed well in the body.

One 1987 study found that the best absorption overall came from zinc picolinate, otherwise known as chelated zinc. 

Vitamin D3

The science on using Vitamin D3 for preventing viral infections is well-grounded, but not so much for SARS-CoV-2. 

I would recommend using it with caution, as some studies suggest Vitamin D3 inhibits the release of pro-inflammatory compounds while others insist Vitamin D3 does the opposite. 

Selenium

The likelihood of successfully using selenium to treat SARS-CoV-2 is unclear, even though it has a similar history to Vitamin D3 of treating viral infections.

Selenium deficiency has often been quoted as risk factor for poor outcomes in viral infections, as certain viral strains can mutate and become highly pathogenic.

However, there is some cause of concern.

Selenium was recently found to be a powerful inhibitor of ACE2, which means there may be some risk in using it.

In short, if someone is deficient in selenium or at high risk of dying from SARS-CoV-2 (via showing signs of respiratory distress), selenium supplementation may be beneficial. 

Melatonin

(Source)

Based on what we know, there is an association between melatonin production and age: As we get older, we produce less melatonin.

Here are several reasons why melatonin may play a helpful role in treating SARS-CoV-2:

Interestingly enough, pregnant women in Wuhan infected with SARS-CoV-2 did not die or develop severe pneumonia.

This is likely because pregnant women produce significantly more melatonin for their age compared to non-pregnant women.

And as for why babies don’t succumb to COVID-19 like older adults do? 

Even though they don’t produce melatonin, they produce a LOT of nitric oxide.

Nicotinamide adenine dinucleotide (NAD+), Resveratrol and Quercetin

NAD+ levels decline with age, and has been investigated as a potential anti-aging target. 

But what makes NAD+ useful in the context of SARS-CoV-2 is how it produces and activations SIRT1. 

SIRT1 blocks the action of mTOR by directly inhibiting it, while also producing AMPK (adenosine monophosphate-activated protein kinase) to further block mTOR. 

However, immune cells also kill off infected cells through a surface protein called CD38, which depletes the NAD+ supply of infected cells. 

For this reason, supplementing with NAD+ could undo the process describe above. 

The same goes for compounds such as resveratrol and quercetin, which also elevate NAD+ levels. 

If someone were to supplement with the above compounds, I would recommend the following two supplements from Liv Health

Renew will directly increase NAD+ production, while Body Shield contains an ample amount of resveratrol and quercetin.

Both of these supplements target and eliminate senescent cells, which will further decrease inflammation in your body.

Metformin

Metformin can serve as a viable way of blocking mTOR without negatively affecting the CD38 mechanism previously discussed. 

It does not require SIRT1 or NAD+ for its mechanism of action to take place. 

I’ve written extensively about this wonderful anti-aging drug in a previous article.

It does require a doctor’s prescription, but it can be obtained from online pharmacies located offshore (here and here).

What Should We Do Regarding COVID-19?

At this point, there are three modes of action you should take…

First, read my article about preparing for a long-lasting coronavirus outbreak. 

If you don’t have all of the supplies and supplements mentioned, get what you can afford. (If you do have them, make sure to keep them in stock so they last several weeks)

Mission critical is oral Vitamin C (Liposomal is the best form)but any capsule formulation will do.

If symptoms present, 500 mg to 2gms C every 30-60 minutes until symptom resolution. (Please understand high dose VC will cause loose stool).

Second, take a look at the article I wrote about the true global impact of the coronavirus.

I am not about FEAR but it is mission-critical to spread FACTUAL AWARENESS of what’s really going on.

Third, re-read this article as many times as necessary (and its various links) to make sure your treatment is appropriate for your present medical condition. 

I send each of you love and light in these uncertain times!

KNOW THIS:

Raising Your Vibration to create bio-systems that are resonant and coherent, will only help your immunity.

We will defeat the enemy and humanity will march on towards the building of a New Golden Age.