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COVID-19: Novel Interventions For A Novel Virus

This article was written by Dr. Kenneth D. Wilgers. All I’ve done is paraphrased what he wrote and condensed it down into the most important information you need to know. 

Everything you will read here is of sound reason and scientific integrity, but none of this information should be considered medical advice. 

This article is meant to help patients in the shortest amount of time, since there are no *official* medically tested interventions as of this writing. 

The Correct Categorization Of The Coronavirus

Before we begin, it’s important to get some facts straight:

  • SARS-CoV is the SARS virus of the 2003 SARS epidemic.
  • SARS-CoV-2 is the current “coronavirus” which is a SARS coronavirus that is closely related to the SARS virus of 2003.
  • COVID-19 is the disease caused by SARS-CoV-2.

As you will see, the novel coronavirus we are observing right now (SARS-CoV-2) is very closely related to the SARS virus (SARS-CoV) that caused the SARS epidemic of 2003.

However, there are some very crucial differences which make the virus – and how it clinically presents itself – unlike anything we’ve ever seen before.

How Is SARS-CoV-2 Transmitted?

There is a reason why SARS-CoV-2 can infect your cells and be transmitted at a far greater rate than the SARS virus of 2003. 

This new virus contains furin cleavage sites on its external spike proteins, whereas the virus of 2003 does not.

Here’s what this means…

These furin cleavage sites interact with furin enzymes on the surface of host cells, thereby gaining access to the cell.

(FYI…Furin is responsible for catalyzing the maturation of biological compounds which are then cleaved to form active proteins in your body)

These furin enzymes are present on every cell line in the human body, which is why SARS-Cov-2 is 1000 times more transmissible than SARS-Cov-2. 

This is also why many infected patients show signs of nervous system dysfunction. 

And if you read my previous article on preparing for the coronavirus outbreak, you know how people with pre-existing diseases are more susceptible to catching the virus and having fatal outcomes. 

Since SARS-CoV-2 gains access to the cell via the angiotensin converting enzyme 2 (ACE2) receptor, some doctors advise patients to stop using drugs which block this receptor. 

When you block the receptor with pharmaceuticals, the cells up-regulate these receptors.

As you can imagine, this increases susceptibility to the virus.

(BTW, this is the same reason why men who use phosphodiesterase 5 inhibitors like Viagra and Cialis find the drug becomes less effective over time) 

Considering how the receptors are found in the lung, kidney and blood vessels, this is why you find the most damage done in those organs.

As always, please consult a licensed healthcare professional about any changes you wish to make to your current medication regime. 

What Happens When SARS-CoV-2 Enters The Cell?

Like any virus, SARS-CoV-2 will “hijack” the components of the host cell so it can replicate itself via the mTOR (mammalian target of rapamycin) enzyme. 

mTOR is primarily responsible for controlling cell growth, and is one of the main reasons why cancer cells grow and replicate far faster than the body can handle. 

SARS-CoV-2 starts replicating until the entire cell is filled to max capacity and it bursts, which releases more copies of the virus to infect other cells. 

For those of you who don’t know, viruses are merely tiny packets of DNA or RNA that can “produce” the proteins needed to build their structure and maintain their function. 

Viruses CANNOT survive without interacting with a host, nor can they replicate without a host. 

The virus then targets specific processes in the cell to trigger an immune response.

While this immune response is healthy when acute (i.e. to try and kill the virus), it is fatal when in excess as it will cause even more damage to the host.

This mechanism of viral infection is very similar to how chronic inflammation acts in the body and becomes the root of many chronic diseases. 

By far, you will see the most damage done by SARS-CoV-2 in the lungs. 

This is why the screening exam for positive cases looks for symptoms such as fever, cough and shortness of breath.

It is also why the majority of deaths caused by SARS-CoV-2 are a result of Adult Respiratory Distress Syndrome (ARDS), a specific type of respiratory failure. 

ARDS develops through the host immune response, and for this reason it becomes incredibly difficult to treat once it has started.

(Source)

The picture above shows how ARDS causes damage to the lungs. 

Chronic inflammation is a very complicated and multifactorial process, but you can already begin to understand how SARS-CoV-2 leads to a very unfavorable outcome in the body. 

The Current Rate Of SARS-CoV-2 Injury Death

(Source)

If you read my article about surviving the coronavirus, the information above is of no surprise to you.’

Older individuals, patients with compromised immune systems, and anybody with pre-existing metabolic is most susceptible to death. 

(Source)

As of March 23, this is where we stand with the OFFICIAL numbers regarding SARS-CoV-2 (of course, the unofficial numbers are probably several magnitudes higher).

 

(Source)

And if you look at the graph above, it is undeniably clear that SARS-CoV-2 is spreading at an exponential rate. 

Proposed Methods For Preventing SARS-CoV-2 And Minimizing Bodily Damage

Health officials and organizations worldwide are scrambling to find new medications and novel uses of existing medications to treat SARS-CoV-2

For example, a recent study was published outlining how a protocol of hydroxychloroquine and azithromycin was effective in a small sample of patients (an antimalarial drug and an antibiotic, respectively).

Another review published in Cell Discovery also discussed how existing pharmaceutical agents can be repurposed for treating SARS-CoV-2. 

What is about to be presented are some thorough research options for preventing infection and/or reducing the degree of injury caused by infection.

NOTE: None of these interventions are endorsed by any medical authority, nor are they recommended by any medical society or advisory board. 

Vitamin C

High doses of Vitamin C (up to 24,000 mg per day) are already being used in China, with several clinical trials (like this one) already being conducted as we speak.

It’s commonly used to treat colds and prevent infections, and has been for several centuries. 

Vitamin C also…

An amazing article from Doris Loh is also an excellent resource on the power of oral vitamin C to combat and stop Covid-19 in it’s tracks.

Jay Campbell made this video on how to dose Vitamin C if one contracts or believes they have initial symptoms of Covid-19.

For the best Vitamin C you can get your hands on, I recommend using Liposomal Vitamin C.

I think it’s safe to say maintenance dosages of C now are anywhere from 1-5gms per day for everyone depending on size and body weight.

Chaga Mushroom

Cliff High now known as the #Chaga_gangsta has been all over the usage of this supplement either in capsule or tea form.

His video’s are about the best on planet earth providing awareness to defeating Covid-19.

This article on the 5 Phases of Covid and their treatment (summarizing Cliff’s work) is also excellent.

Nitric Oxide (NO)

Nitric oxide helps inhibit the production of pro-inflammatory compounds, thereby protecting against ARDS.

I would not recommend the use of pre-workout supplements, as they also contain large amounts of caffeine. 

Foods such as black pepper, pine bark extract, beet root extract, citrulline and arginine can help boost nitric oxide production as well.

Tadalafil at a precise micro-dosage of 2.5-5 mg daily can also increase nitric oxide production.

If you want a supplement specifically engineered to increase production of nitric oxide, NEONOX comes highly recommended.  

Zinc

Zinc has been proven to have beneficial effects for treating cold sores and common colds.

However, it can exhibit antiviral activity against SARS-CoV (SARS 2003), H1N1, HIV, papillomavirus, and many other viruses. 

There are several forms of zinc available as supplements.

I personally recommend zinc gluconate as it gets absorbed well in the body.

One 1987 study found that the best absorption overall came from zinc picolinate, otherwise known as chelated zinc. 

Vitamin D3

The science on using Vitamin D3 for preventing viral infections is well-grounded, but not so much for SARS-CoV-2. 

I would recommend using it with caution, as some studies suggest Vitamin D3 inhibits the release of pro-inflammatory compounds while others insist Vitamin D3 does the opposite. 

Selenium

The likelihood of successfully using selenium to treat SARS-CoV-2 is unclear, even though it has a similar history to Vitamin D3 of treating viral infections.

Selenium deficiency has often been quoted as risk factor for poor outcomes in viral infections, as certain viral strains can mutate and become highly pathogenic.

However, there is some cause of concern.

Selenium was recently found to be a powerful inhibitor of ACE2, which means there may be some risk in using it.

In short, if someone is deficient in selenium or at high risk of dying from SARS-CoV-2 (via showing signs of respiratory distress), selenium supplementation may be beneficial. 

Melatonin

(Source)

Based on what we know, there is an association between melatonin production and age: As we get older, we produce less melatonin.

Here are several reasons why melatonin may play a helpful role in treating SARS-CoV-2:

Interestingly enough, pregnant women in Wuhan infected with SARS-CoV-2 did not die or develop severe pneumonia.

This is likely because pregnant women produce significantly more melatonin for their age compared to non-pregnant women.

And as for why babies don’t succumb to COVID-19 like older adults do? 

Even though they don’t produce melatonin, they produce a LOT of nitric oxide.

Nicotinamide adenine dinucleotide (NAD+), Resveratrol and Quercetin

NAD+ levels decline with age, and has been investigated as a potential anti-aging target. 

But what makes NAD+ useful in the context of SARS-CoV-2 is how it produces and activations SIRT1. 

SIRT1 blocks the action of mTOR by directly inhibiting it, while also producing AMPK (adenosine monophosphate-activated protein kinase) to further block mTOR. 

However, immune cells also kill off infected cells through a surface protein called CD38, which depletes the NAD+ supply of infected cells. 

For this reason, supplementing with NAD+ could undo the process describe above. 

The same goes for compounds such as resveratrol and quercetin, which also elevate NAD+ levels. 

If someone were to supplement with the above compounds, I would recommend the following two supplements from Liv Health

Renew will directly increase NAD+ production, while Body Shield contains an ample amount of resveratrol and quercetin.

Both of these supplements target and eliminate senescent cells, which will further decrease inflammation in your body.

Metformin

Metformin can serve as a viable way of blocking mTOR without negatively affecting the CD38 mechanism previously discussed. 

It does not require SIRT1 or NAD+ for its mechanism of action to take place. 

I’ve written extensively about this wonderful anti-aging drug in a previous article.

It does require a doctor’s prescription, but it can be obtained from online pharmacies located offshore (here and here).

What Should We Do Regarding COVID-19?

At this point, there are three modes of action you should take…

First, read my article about preparing for a long-lasting coronavirus outbreak. 

If you don’t have all of the supplies and supplements mentioned, get what you can afford. (If you do have them, make sure to keep them in stock so they last several weeks)

Mission critical is oral Vitamin C (Liposomal is the best form)but any capsule formulation will do.

If symptoms present, 500 mg to 2gms C every 30-60 minutes until symptom resolution. (Please understand high dose VC will cause loose stool).

Second, take a look at the article I wrote about the true global impact of the coronavirus.

I am not about FEAR but it is mission-critical to spread FACTUAL AWARENESS of what’s really going on.

Third, re-read this article as many times as necessary (and its various links) to make sure your treatment is appropriate for your present medical condition. 

I send each of you love and light in these uncertain times!

KNOW THIS:

Raising Your Vibration to create bio-systems that are resonant and coherent, will only help your immunity.

We will defeat the enemy and humanity will march on towards the building of a New Golden Age.

 

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